Ctnnd1
- Known as:
- Ctnnd1
- Catalog number:
- 046672A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- Ctnnd1
Related genes to: Ctnnd1
- Gene:
- CTNND1 NIH gene
- Name:
- catenin delta 1
- Previous symbol:
- CTNND
- Synonyms:
- KIAA0384, p120, p120cas, p120ctn
- Chromosome:
- 11q12.1
- Locus Type:
- gene with protein product
- Date approved:
- 1995-09-18
- Date modifiied:
- 2015-11-19
Related products to: Ctnnd1
anti-CTNND1 / p120CTN (C-Terminus)Anti-CTNND1, Rabbit Polyclonal to CTNND1, Isotype , Host RabbitBovine Catenin delta-1(CTNND1) ELISA kitBovine enin delta-1(CTNND1) ELISA kitCadherin-associated Src substrate,CAS,Catenin delta-1,Catns,Ctnnd1,Kiaa0384,Mouse,Mus musculus,p120 catenin,p120(cas),p120(ctn)Cadherin-associated Src substrate,CAS,Catenin delta-1,CTNND1,Homo sapiens,Human,KIAA0384,p120 catenin,p120(cas),p120(ctn)Canine Catenin delta-1(CTNND1) ELISA kitCanine Catenin delta-1(CTNND1) ELISA kitCanine enin delta-1(CTNND1) ELISA kitCanine enin delta-1(CTNND1) ELISA kitcatenin (cadherin-associated protein). delta 1 (CTNND1) - Mouse monoclonal anti-human CTNND1 antibody; p120 catenin; p120(ctn); Cadherin-associated Src substrate; CAS; p120(cas) MonoclonalCatenin delta 1 (CTNND1)ELISA Kit, HumanCatenin δ-1 Polyclonal Antibody, Reactivity: H M R, Gene ID: 1500, Synonyms: CTNND1Catenin δ-1 Polyclonal Antibody, Reactivity: H M R, Gene ID: 1500, Synonyms: CTNND1Catenin δ-1 Polyclonal Antibody, Reactivity: H M R, Gene ID: 1500, Synonyms: CTNND1 Related articles to: Ctnnd1
- Is E-cadherin (CDH1) expressed on the free apical surface of endometrial epithelial cells (EECs) involved in embryo attachment? - Source: PubMed
Ruan HanzhangChen Andy Chun HangXue YuxuanLee Kai ChuenFong Sze WanQiu QiTan YongqiFeng YingLee Cheuk LunHua RenwuHuang JunrongWang TianrenXu YanwenLee Kai-FaiXi NingLi Raymond Hang WunNg Ernest Hung YuYeung William Shu BiuLee Yin Lau - Familial exudative vitreoretinopathy (FEVR) is an inherited eye disease characterised by the incomplete development of the retinal vasculature. Over 10 genes have been associated with FEVR, but there are still a substantial number of genetically unsolved cases. The aim of this study was to analyse whole genome sequencing (WGS) data from the FEVR cases in the Genomics England (GEL) 100 000 genomes project to identify the causative variants. - Source: PubMed
Publication date: 2026/02/20
Sun DongHenderson Robert HClement EmmaMichaelides MichelKalitzeos AngelosWright Genevieve AMcloone EibhlinInglehearn ChrisPoulter James AToomes Carmel - The intratumor microenvironment shapes the metastatic potential of cancer cells and their susceptibility to any immune response. Yet, the nature of the signals within the microenvironment that control anticancer immunity and how they are regulated is poorly understood. Here, using melanoma as a model, we investigate the involvement in metastatic dissemination and the immune-modulatory microenvironment of Protein S-Acyl Transferases as an underexplored class of potential therapeutic targets. We find that ZDHHC13 suppresses metastatic dissemination by palmitoylation of CTNND1, leading to stabilization of E-cadherin. Importantly, ZDHHC13 also reshapes the tumor immune microenvironment by suppressing lysophosphatidylcholine (LPC) synthesis in melanoma cells, leading to inhibition of M2-like tumor-associated macrophages that we show degrade E-cadherin via MMP12 expression. Consequently, ZDHHC13 activity suppresses tumor growth and metastasis in immunocompetent mice. Our study highlights the therapeutic potential of targeting the ZDHHC13-E-cadherin axis and its downstream metabolic and immune-modulatory mechanisms, offering additional strategies to inhibit melanoma progression and metastasis. - Source: PubMed
Publication date: 2025/09/30
Li HongjinLyu JiankeSun YuYin ChengqianLi YuewenChen WeiqiangFoo Suan-SinWu XianfangGoding Colin RChen Shuyang - Panitumumab shows limited clinical benefit in colorectal cancer (CRC), and reliable predictive biomarkers to guide patient selection remain lacking. To address this gap, we investigated molecular determinants of therapeutic response using tumor samples from patients with primary and metastatic CRC. By integrating PIMS-based metastatic classification, NPOT interaction profiling and quantitative proteomics, this study aimed to identify response-associated pathways and potential prognostic biomarkers that could support improved stratification for panitumumab therapy. - Source: PubMed
Quartier AngeliqueSanin Ahmed YNagelschmitz JuliaSchneider JustineShi WenjieWartmann ThomasDölling MaximilianStelter FrederikeAndric MihailoCroner Roland SEftekhari PierreKahlert Ulf D - In the original publication [...]. - Source: PubMed
Publication date: 2025/11/17
Lin QunFang XiaolinLiang GehaoLuo QingCen YinghuanShi YuJia ShijieLi JuanmeiYang WenqianSanders Andrew JGong ChangJiang Wenguo