Cacna1c
- Known as:
- Cacna1c
- Catalog number:
- 043084A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- Cacna1c
Related genes to: Cacna1c
- Gene:
- CACNA1C NIH gene
- Name:
- calcium voltage-gated channel subunit alpha1 C
- Previous symbol:
- CCHL1A1, CACNL1A1
- Synonyms:
- Cav1.2, CACH2, CACN2, TS, LQT8
- Chromosome:
- 12p13.33
- Locus Type:
- gene with protein product
- Date approved:
- 1991-01-30
- Date modifiied:
- 2019-04-23
Related products to: Cacna1c
Anti-CACNA1Canti-CACNA1C / Cav1.2anti-CACNA1C / Cav1.2Antibodies: CACNA1C HOST: Goat Clonality: pAbBovine Voltage-dependent L-type calcium channel subunit alpha-1C(CACNA1C) ELISA kitCACB-receptor,CACH2,CACN2,CACNA1C,CACNL1A1,Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle,CCHL1A1,Oryctolagus cuniculus,Rabbit,Smooth muscle calcium channel blocker receptor,VCACH2,CACN2,CACNA1C,CACNL1A1,Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle,CCHL1A1,Homo sapiens,Human,Voltage-dependent L-type calcium channel subunit alpha-1C,Voltage-gatedCach2,Cacn2,Cacna1c,Cacnl1a1,Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle,Cchl1a1,MBC,MELC-CC,Mouse,Mouse brain class C,Mus musculus,Voltage-dependent L-type calcium channelCach2,Cacn2,Cacna1c,Cacnl1a1,Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle,Cchl1a1,Rat,Rat brain class C,Rattus norvegicus,RBC,Voltage-dependent L-type calcium channel subuniCACNA1A Gene calcium channel, voltage-dependent, P_Q type, alpha 1A subunitCACNA1C AntibodyCACNA1C antibody Ab host: RabbitCACNA1C (aa 1150_1200)CACNA1C (aa 1150_1200)CACNA1C (aa 1450_1500) Related articles to: Cacna1c
- variants have been identified in cardiac arrhythmias and developmental disorders (DD). Here, we aimed to explore the association between and epilepsy and the mechanism underlying phenotypic heterogeneity. - Source: PubMed
Publication date: 2026/08/06
Li Yan-FangMo PeiZhang Lan-ZhenZhou Xin-LongZhu Wen-YuZhu Jun-HuiLiao Shu-HongChen Ya-TingDeng WeiwenZhang Dong-MingLiu Xiao-RongChen Yong-JunLiao Wei-PingWang JieCheng Chuan-Fang - Calcium channel blockers (CCBs) show notable interindividual variability in antihypertensive response. This study evaluated the association of a pharmacogenomics (PGx)-guided antihypertensive strategy incorporating rs2238032 and rs776746 with short-term blood pressure (BP) outcomes among Chinese patients with hypertension receiving CCB-containing regimens. - Source: PubMed
Publication date: 2026/07/30
Deng KunhongGuo YanZhang YaxinQiu HuiKuang YunWang YuMeng DiZhang MengGuo Chengxian - CACNA1C-related disorder (CRD), a severe multisystem disorder caused by variants of gene, presents significant diagnostic and management challenges due to its rarity and variable expressivity. This study leverages a detailed longitudinal case report and comprehensive literature review to expand the phenotypic spectrum of CRD with Timothy syndrome (TS) features associated with the NM_001129830.1: c.3061 T > C (p.Cys1021Arg) variant. We describe an individual with CRD exhibiting a severe multisystem phenotype including classic features like syndactyly, profound neurological symptoms, and cardiac arrhythmias. Critically, our detailed clinical and genetic analysis identified previously undocumented features for this specific variant: cerebral infarction, as well as a combined T-cell and B-cell immunodeficiency characterized by specific lymphocyte dysregulation. These novel findings necessitate refined diagnostic protocols and tailored management strategies. By redefining CRD with TS features as a profoundly multisystem disorder, this expanded understanding facilitates improved prognostication, genetic counseling, and targeted therapeutic interventions, aiming to transform management from unpredictable complications into predictable, preventable components, ultimately enhancing quality of life and survival. - Source: PubMed
Publication date: 2026/07/13
Jiang CongshanZhou YafeiZhang SiyuLu XiaoxiaoLi XiaZhang Yanmin - Suicidal behavior is a complex and multifactorial phenomenon rooted in both psychological and biological mechanisms. In recent years, there has been an increasing focus on epigenetic factors, which modulate the influence of environmental factors on the expression of genes associated with emotional and cognitive regulation. - Source: PubMed
Publication date: 2026/03/02
Tussupova AruzhanTatayeva RozaKoygeldinova SholpanBazarbayeva ZhannatSembaeva ZhibekMussina Aiman - Mood and psychotic disorders are associated with disrupted circadian rhythms in sleep and activity. While mood and psychosis risk-associated genes (MPRGs) have been linked with sleep and circadian phenotypes, their contributions to molecular clock pathways and cellular circadian rhythms remain unknown. - Source: PubMed
Publication date: 2026/07/27
Xue XiangningAdelsheim ZoeGorczyca Michael TWei HeatherLeone Michael JLogan Ryan WMcCarthy Michael J