AVEN
- Known as:
- AVEN
- Catalog number:
- 002317A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- AVEN
Related genes to: AVEN
- Gene:
- AVEN NIH gene
- Name:
- apoptosis and caspase activation inhibitor
- Previous symbol:
- -
- Synonyms:
- PDCD12
- Chromosome:
- 15q14
- Locus Type:
- gene with protein product
- Date approved:
- 2002-09-17
- Date modifiied:
- 2016-10-05
Related products to: AVEN
Related articles to: AVEN
- The "brain-eating amoeba" dwells in ponds where it normally feeds on bacteria, but if it enters the brain it can cause a deadly infection. To establish infection, must migrate through different environments-along olfactory axons, through openings in the cribriform plate, and within brain tissue-yet how it does so remains unknown. As a model for migration within these environments, we examine how its nonpathogenic relative, , navigates environments of distinct geometries. We show that uses both actin-rich protrusions and membrane blebs to crawl across or between flat surfaces. We also explore how interact with narrow channels and find that, unlike amoebae that we show frequently disengage from channel interfaces, amoebae probe channels until they enter. Once inside, crawls quickly (>50 μm/min) and unidirectionally over long distances (>1 mm) using only bleb-based motility. We also introduced to granular hydrogel matrices that mimic pond sediments and found that cells readily enter and migrate through these three-dimensional matrices using both blebs and lamellar protrusions. Although cells in matrices showed lower persistence at short timescales, longer time scales correlate with increased persistence, suggesting cells may retain memory of past orientation. We propose that pond life may select for three behaviors that prime for pathogenesis: memory-guided motility that would facilitate exploration of sinus cavities, confinement-seeking ("claustrophilia") that would promote entry into narrow passages along olfactory axons, and persistent bleb-based migration that would allow rapid transit along axons to the brain. - Source: PubMed
Publication date: 2026/09/10
Velle Katrina BRamaswamy MeeraHokmabad Babak VajdiMartín-Pérez TaniaCarrasco Teodoro TapiaCallahan William SKim Harrison SLarkin Emily MElZafarany Abdurrahman HJacques Samantha MDatta Sujit SEdwards MarcFritz-Laylin Lillian K - Laser Speckle Flowgraphy (LSFG) is a non-invasive imaging technology that quantitatively evaluates retinal and choroidal blood flow by analyzing speckle patterns generated by laser light scattering. Compared with OCT-A, which provides detailed visualization of retinal and choroidal microvascular architecture, LSFG offers dynamic quantitative information on ocular blood flow. This systematic review summarizes the application of LSFG in two major vascular diseases: retinal vein occlusion (RVO), and central serous chorioretinopathy (CSCR). - Source: PubMed
Publication date: 2026/09/04
Bellucci CarloVirgili MedeaRomano AlessandraCarta ArturoMora Paolo - The current state of research on the oxidative dehydrogenation of ethylbenzene and 4-vinylcyclohexene to styrene in the presence of dioxygen and carbon dioxide is reviewed. The high efficiency and potential of producing styrene from 4-vinylcyclohexene (a dimerization/condensation adduct of buta-1,3-diene) using carbon dioxide over oxide and zeolite catalysts modified with selected rare-earth metal (REM) oxides are demonstrated. Experimental findings are presented and potential reaction pathways are discussed. Particular emphasis is placed on the redox and acid-base properties of the catalysts and their critical role in catalyst selection for these processes. - Source: PubMed
Publication date: 2026/08/30
Alimardanov Hafiz MutallimJalilova Arzu Akif - Although recent developments have improved clarity on the characteristics of high-quality risk science, there is recognition that many of those characteristics relate to specific tasks taken by the risk analyst. However, the effectiveness of risk analysis and management often relies on both internal risk team activities and other external systemic factors. This article leverages reports on past risk events to develop new knowledge on systemic factors that have frequently appeared in connection with major risk events, including whistleblower dynamics, lack of accountability, financial aspects, corruption or fraudulent behavior, scientific disagreement, and political influence and lobbying. Such factors are not typically addressed in existing risk study quality indicators or in training and professional expectations for risk analysts. We explore this issue by introducing the reverse risk register concept to study the role of those factors in past risk events. We utilize the analysis presented in this article to support several areas for risk analyst training and guidance. The findings of this article suggest that although these systemic factors are not typically within the risk analyst's professional responsibilities, awareness and standardized thinking about these areas will improve the risk analyst's perspective within their professional duties. The findings can also help risk analysts, decision-makers, and managers consider whether such factors are present in their organizations and how their presence might influence the risk management process or the risk itself. This article will be of interest to risk analysts, industry professionals, and policymakers. - Source: PubMed
Thekdi ShitalAven Terje - Pulsed radiofrequency of the lumbar dorsal root ganglion (DRG-PRF) is a minimally invasive treatment for chronic radicular pain, but outcomes vary substantially and validated prediction models to guide patient selection are lacking. The aim of this study was to develop and internally validate a multivariable prediction model identifying patients most likely to achieve treatment success following lumbar DRG-PRF. - Source: PubMed
Publication date: 2026/08/24
Leoni Matteo Luigi GiuseppeMercieri MarcoMagnoni SandraBianco Giuliano LoHasoon JamalViswanath OmarFarì GiacomoChelo GiuseppinaVarrassi Giustino