ANKRD10
- Known as:
- ANKRD10
- Catalog number:
- 001602A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- ANKRD10
Related genes to: ANKRD10
- Gene:
- ANKRD10 NIH gene
- Name:
- ankyrin repeat domain 10
- Previous symbol:
- -
- Synonyms:
- FLJ20093
- Chromosome:
- 13q34
- Locus Type:
- gene with protein product
- Date approved:
- 2003-01-16
- Date modifiied:
- 2016-10-05
Related products to: ANKRD10
Related articles to: ANKRD10
- Substantial unexplained heritability remains for pathogenic inherited retinal disease (IRD) variants. Application of genome-wide association studies (GWAS) could help identify causal genes in rare diseases. - Source: PubMed
Publication date: 2026/07/30
Kraatari-Tiri MinnaIshtiaq HinaTyrmi JaakkoLin SiyingValkama AndrianaTiirikka TimoÄikäs SaraLähteenoja LauraWright GenevieveSchiff ElenaJestin AleksandrWebster Andrew RMahroo Omar AMichaelides MichelMoilanen JukkaPylkäs KatriKettunen JohannesArno GavinFalck AuraMantere TuomoRahikkala Elisa - Stress involves complex interactions between the brain and endocrine systems, but the gene-level processes and genetic factors mediating these responses remain unclear. This study investigates gene expression patterns and allele-specific expression (ASE) in key limbic, diencephalon and endocrine tissues to better understand stress adaptation at the molecular level. - Source: PubMed
Publication date: 2025/09/03
Iqbal Muhammad ArsalanHadlich FriederReyer HenryOster MichaelTrakooljul NaresWimmers KlausPonsuksili Siriluck - Melanoma exhibited a poor prognosis due to its aggression and heterogeneity. The effect of glutamate metabolism promoting tumor progression on cutaneous melanoma remains unknown. Herein, glutamine metabolism-related genes (GRGs) were identified followed by constructing a prognostic model for melanoma via bioinformatics analysis. - Source: PubMed
Publication date: 2025/08/20
Hu HongyanYang JingMiao JinLi ChenWang CaoRan FengmingZou JieZhang YiZhao LiufangZhao WentaoAi Conghui - RNA-binding proteins (RBPs) are pivotal mediators of the alternative splicing (AS) machinery of pre-mRNA. Research has demonstrated that the AS process is significantly dysregulated and plays a crucial role in bladder cancer (BLCA). We conducted comprehensive screening and analysis of the TCGA-BLCA cohort, specifically focusing on genes with significant differences in expression levels between carcinoma and adjacent non-cancerous tissues. Among the 500 differentially expressed genes, 5 RNA-binding proteins were identified. Only the RNA-binding protein with multiple splicing (RBPMS) demonstrated a consistent downregulation in BLCA and was correlated with an unfavorable prognosis for affected patients. Subsequent experiments revealed that RBPMS exerted inhibitory effects on the epithelial-mesenchymal transition (EMT) pathway and the migratory potential of BLCA cells. RNA-Seq analysis identified ANKRD10 as a key target mRNA regulated by RBPMS in BLCA. RBPMS depletion in BLCA cells resulted in AS of ANKRD10 and increased ANKRD10-2 expression. ANKRD10-2 functioned as a transcriptional co-activator of MYC proteins, thereby augmenting their transcriptional activity. Furthermore, ANKRD10-2 knockdown significantly rescued the migration enhancement induced by RBPMS depletion in BLCA cells. Taken together, this study revealed a mechanism whereby RBPMS suppresses the migration and invasion of BLCA cells by attenuating MYC pathway activity via the AS of ANKRD10. - Source: PubMed
Publication date: 2025/03/05
Yu JingtianChen LiangWang GangQian KaiyuWeng HongYang ZhonghuaZheng HangLu Mengxin - Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma worldwide with a high degree of heterogeneity. Cuproptosis and immunogenic cell death (ICD) have been considered to be vital for tumor progression. However, current understanding of cuproptosis and immunogenic cell death in DLBCL is still very limited. We aim to explore a prognostic model combining cuproptosis and immunogenic cell death in DLBCL. - Source: PubMed
Publication date: 2024/01/26
Wang NanaShi ShanshanLi MoranYu XiaoningMa Guangxin