ANKRD7
- Known as:
- ANKRD7
- Catalog number:
- 001600A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- ANKRD7
Related genes to: ANKRD7
- Gene:
- ANKRD7 NIH gene
- Name:
- ankyrin repeat domain 7
- Previous symbol:
- -
- Synonyms:
- TSA806
- Chromosome:
- 7q31.31
- Locus Type:
- gene with protein product
- Date approved:
- 2002-07-22
- Date modifiied:
- 2018-05-03
Related products to: ANKRD7
Related articles to: ANKRD7
- To develop a robust quantitative method for assessing testicular spermatogenic capacity in patients with idiopathic non-obstructive azoospermia (iNOA), leveraging single-cell RNA sequencing to enhance diagnostic precision and inform personalized treatment strategies. - Source: PubMed
Publication date: 2025/07/19
Ding ShuFang YangyiZhang LiHong KaiQiao JieChen Yidong - Excreta traits comprise a very important characteristic in breeding that have been neglected for a long time. With the growth of intensive pig farming, plenty of environment problems have been raised, and people have begun to pay attention to pig excreta behaviors from genetics and breeding perspectives. However, the genetic architecture of excreta traits remains unclear. To investigate the genetic architecture of excreta traits in pigs, eight excreta traits and feed conversion ratio (FCR) were analyzed in this study. We performed genome-wide association studies (GWASs) on 213 Yorkshire pigs and estimated genetic parameters for a total number of 290 pigs, comprising 213 Yorkshire, 52 Landrace and 25 Duroc. After analysis, eight and 22 genome-wide significant SNPs were detected for FCR and the eight excreta traits in single-trait GWASs separately, and 18 were detected in a multi-trait meta-analysis for excreta traits, six of which were detected in both the single-trait and the multi-trait GWAS. Eighty, 182 and 133 genes were detected within 1 Mb of the genome-wide significant SNPs for FCR, excreta traits and multi-trait meta-analysis, respectively. Five candidate genes (BCKDC, DBT, ANKRD7, SHPRH and HCRT) with biochemical and physiological effects relevant to feed efficiency and excreta traits might be interesting markers for future breeding. Meanwhile, functional enrichment analysis indicates that most of the significant pathways are associated with the glutathione catabolic process, DNA topological change and replication fork protection complex. This study reveals the architecture of excreta traits in commercial pigs and offers an opportunity for decreasing the pollution from excreta using genomic selection in pigs. - Source: PubMed
Publication date: 2023/04/11
Wang JunjianYang HuaweiChen ShaokangLi WeiningYu JianHu ZhengzhengZhuo YueHuang QianqianLiu ZhenZhou LeiWu JianliangWang ZhaojunGuo FengYun PengWang XiaofengLiu Jian-Feng - Neoadjuvant chemoradiotherapy (nCRT) followed by surgery benefits survival for patients with esophageal squamous cell carcinomas (ESCC) compared with surgery alone, but the clinical outcomes of nCRT are heterogeneous. This study aimed to elucidate transcriptional factor (TF) regulation network and competitive endogenous RNA (ceRNA) network determining response of ESCC to nCRT. - Source: PubMed
Publication date: 2019/03/29
Shao MingruiLi Wenya - Thyroid antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb) are key markers of Hashimoto's thyroiditis (HT), the most common autoimmune thyroid disorder. Genetic determinants of thyroid antibodies are still poorly known, especially as they were not studied in patients with thyroid diseases. We performed the first genome-wide association analysis of thyroid antibodies in 430 HT patients that may be considered as population extremes for thyroid antibodies distribution. We detected two suggestively associated genetic variants with TgAb, rs6972286 close to ANKRD7 and LSM8 (P = 2.34 × 10) and rs756763 inside CA10 (P = 6.05 × 10), and one with TPOAb, rs12507813 positioned between TRIM61 and TRIM60 (P = 4.95 × 10). Bivariate analysis resulted with three suggestively associated genetic variants that predispose to both antibodies: rs13190616 inside RP11-138J23.1 (P = 2.01 × 10), rs561030786 close to DUBR (P = 7.33 × 10) and rs12713034 inside FSHR (P = 7.66 × 10). All identified genomic regions have a substantial literature record of involvement with female-related traits, immune-mediated diseases and personality traits that are all characterized by increased thyroid antibody levels. Our findings demonstrate the existence of genetic overlap between thyroid autoimmunity in HT and different non-thyroid diseases characterized by the presence of thyroid antibodies. We also suggest that genetic variants that regulate antibody levels may differ between HT patients and individuals with normal thyroid function. - Source: PubMed
Publication date: 2019/03/29
Brčić LukaBarić AnaGračan SandaTorlak VeselaBrekalo MarkoŠkrabić VeselinZemunik TatijanaBarbalić MajaPunda AnteBoraska Perica Vesna - It is uncommon for cervical cancer patients to be diagnosed without a human papillomavirus (HPV) infection. As prophylactic vaccines against high-risk HPV types are an ineffective preventive measure for these patients it is essential to identify differential biomarkers that may be associated with detection, prognosis and novel targeted therapies. The objective of this study was to compare the two entities, HPV+ and HPV- cervical cancers, based on TCGA public data. - Source: PubMed
Publication date: 2018/12/20
Zhang LiyaJiang YiLu XiaofanZhao HuilingChen ChenWang YaoyanHu WenjunZhu YueYan HangyuYan Fangrong