AFAP1L1
- Known as:
- AFAP1L1
- Catalog number:
- 001262A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- AFAP1L1
Related genes to: AFAP1L1
- Gene:
- AFAP1L1 NIH gene
- Name:
- actin filament associated protein 1 like 1
- Previous symbol:
- -
- Synonyms:
- FLJ36748
- Chromosome:
- 5q32
- Locus Type:
- gene with protein product
- Date approved:
- 2007-02-07
- Date modifiied:
- 2019-03-26
Related products to: AFAP1L1
Related articles to: AFAP1L1
- Clear cell renal cell carcinoma (ccRCC) accounts for over 75% of all renal cancer and contributes significantly to cancer-associated mortality. This study aims to identify a new ccRCC biomarker. - Source: PubMed
Publication date: 2026/03/23
Yan QiaopingZhang BinbinYu YunhanSi YuewenZhang YuanYe ZijianZhang QingmingWu WenlingLuo XuegangXie Biao - Evidence for the microbiome's role in human health and disease has been piling up ever since the human microbiome project. The composition of one's microbiome can have a major effect on one's risk of developing cancer and the nature of how cancer develops. Several estimates suggest the percentage of cancer cases that can be attributed to microorganisms at around 15%. In addition, researchers are still trying to figure out how the microbiota, and the gut microbiota in particular, affects how a patient responds to chemotherapy, immunotherapy, and radiotherapy. In this light, we conducted an in-depth bioinformatics analysis of the gut microbiota- RCCstem cells axis, utilizing python-based programme and enrichment databases to analyses data from many sources, including clinical data, transcription factors, kinases and gene expression profile of RCCstem cells. Five genes, including SLC16A6, CPNE5, AFAP1L1, SCARF1, and NOTCH4, were shown to be shared by the hub gut microbiota and extracellular proteins. Patients with RCCstem cells had a disproportionately high number of certain types of bacteria. In patients expression profile have high CPNE5, AFAP1L1, SCARF1, and NOTCH4 expression. RCCsurvival rates are reduced by roughly 50% due to all of the genes involved. Also, the Actinobacteria and Gammaproteobacteria possible role in renal cancer development via relation to cancer stem cells. The gut microbiota and its components were considered for their possible relevance in the development of RCC. - Source: PubMed
Publication date: 2025/12/09
Alimoradi EhsanHashemnejad Mohammad AminEtemad SarehArabi MaryamBereimipour Ahmad - Diabetic retinopathy affects a substantial proportion of individuals with diabetes and, if not treated, may lead to acquired visual impairment or even blindness. An improved comprehension of the genetics of diabetic retinopathy (DR) is crucial in understanding the disease mechanisms. We aimed to identify rare and low-frequency variants predisposing to severe DR (SDR) in type 1 diabetes. - Source: PubMed
Vuori NadjaAntikainen Anni AHaukka Jani KHarjutsalo ValmaGroop Per-HenrikSandholm Niina - Nasopharyngeal carcinoma (NPC) is a prevalent form of cancer in Southeast Asia, characterized by distinctive epidemiological attributes, and its occurrence is influenced by factors such as race, age, and gender. Prior research has highlighted the potential of serum microRNA (miRNA) profiling as a non-invasive biomarker for cancer detection. The objective of this study was to ascertain the miRNAs that are specifically linked to the diagnosis of NPC. - Source: PubMed
Publication date: 2025/06/26
Li XutaiGe ZhenjianChen WenkangLi YingqiLin ShengjieWu YutongZhang PengwuZhou HuimeiLai Yongqing - Gastric cancer (GC) has a poor prognosis, considerable cellular heterogeneity, and ranks fifth among malignant tumours. Understanding the tumour microenvironment (TME) and intra-tumor heterogeneity (ITH) may lead to the development of novel GC treatments. - Source: PubMed
Publication date: 2025/01/06
Ma QiGao JieHui YuanZhang Zhi-MingQiao Yu-JieYang Bin-FengGong TingZhao Duo-MingHuang Bang-Rong