ACAT1
- Known as:
- ACAT1
- Catalog number:
- 000987A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- ACAT1
Related genes to: ACAT1
- Gene:
- ACAT1 NIH gene
- Name:
- acetyl-CoA acetyltransferase 1
- Previous symbol:
- ACAT
- Synonyms:
- THIL
- Chromosome:
- 11q22.3
- Locus Type:
- gene with protein product
- Date approved:
- 1991-08-12
- Date modifiied:
- 2014-11-19
Related products to: ACAT1
ACACT,ACACT1,ACAT,ACAT1,ACAT-1,Acyl-coenzyme A cholesterol acyltransferase 1,Cholesterol acyltransferase 1,Homo sapiens,Human,SOAT,SOAT1,STAT,Sterol O-acyltransferase 1ACAP2 Gene ArfGAP with coiled-coil, ankyrin repeat and PH domains 2ACAT,ACAT1,Acetoacetyl-CoA thiolase,Acetyl-CoA acetyltransferase, mitochondrial,Homo sapiens,Human,MAT,T2acat1 antibody Isotype IgG Host RabbitACAT1 MAT antibody Ab host: RabbitACAT1 MAT antibody Ab host: RabbitACAT1 MAT (253-266) antibody Ab host: GoatACAT1 MAT (257-269) antibody Ab host: GoatACAT1 MAT (C-term) Ig antibody Ab host: RabbitACAT1 MAT (N-term) IgG antibody Ab host: MouseACAT1 MAT IgG antibody Ab host: RabbitACAT1 MAT IgG antibody Ab host: RabbitACAT1 MAT IgG antibody Ab host: RabbitACAT1 MAT IgG1 antibody Ab host: MouseACAT1 MAT IgG1 antibody Ab host: Mouse Related articles to: ACAT1
- Clear cell renal cell carcinoma (ccRCC) is hallmarked by profound metabolic reprogramming; however, its intricate crosstalk with the tumor immune microenvironment (TIME) and its clinical ramifications remain inadequately elucidated. This study aims to systematically decipher the metabolic-immune interplay in ccRCC through multi-omics integration, with the goal of identifying robust prognostic biomarkers and actionable therapeutic vulnerabilities. - Source: PubMed
Peng YiQin SuobingLi XiwenWan LijunGuan Rijian - Eyelid sebaceous gland carcinoma (SGC) is a rare and aggressive malignancy of the eyelids. Dysregulated cholesterol metabolism has been found to be involved in pathogenesis of various cancers including glioblastoma, breast, prostate, and pancreatic cancer. The role of cholesterol metabolism in SGC and its molecular characterization remains unexplored. This study evaluates the clinical significance of the expression of a key enzyme involved in cholesterol metabolism, acyl-CoA cholesterol acyltransferase 1 (ACAT1) in eyelid SGC. - Source: PubMed
Publication date: 2026/08/31
Rafat SaharSen SeemaChosdol KunzangBakhshi SameerKashyap SeemaPushker Neelam - Beta-ketothiolase deficiency (BKTD) is a rare autosomal recessive metabolic disorder affecting isoleucine catabolism and ketone body utilization, demonstrating marked clinical and biochemical heterogeneity. This study aims to characterize the longitudinal clinical, biochemical, and genetic features of a single-center BKTD cohort and evaluate phase-dependent dynamics in metabolic biomarkers during acute crises and stable follow-up periods. - Source: PubMed
Publication date: 2026/08/25
Ergun Nurcan ÜçüncüCoşkun NihalAslantaş MerveKöse Meyrem Aybike Kurtbeyoğlu - Beta-ketothiolase deficiency (BKTD) is a rare genetic metabolic disorder caused by variants in the ACAT1 gene. It can induce severe metabolic acidosis, which may be life-threatening. This study reports two critically ill children with newly diagnosed BKTD and includes a literature review to comprehensively depict the clinical, biochemical, and genetic profiles of BKTD patients in China. - Source: PubMed
Publication date: 2026/08/19
Deng XiLi XintingLiu HaoranWang TaoTang FangTan QingtiFeng YuLuo Xiaoli - Major depressive disorder (MDD) and obesity are intersecting global crises. Despite observational links, a clinical paradox persists: antidepressants often improve metabolic status, while weight loss rarely alleviates core depressive symptoms. This prompts closer examination of whether the depression-obesity relationship reflects asymmetric genetic architecture, shared liability, or statistical constraints that obscure definitive conclusions. - Source: PubMed
Publication date: 2026/08/07
Li XingpeiChen ChunlinLi HuibingHe YiruTang KailangLai GuanqiaoYang ZiyangChen WushuYang Huihui