ABI3
- Known as:
- ABI3
- Catalog number:
- 000956A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- ABI3
Related genes to: ABI3
- Gene:
- ABI3 NIH gene
- Name:
- ABI family member 3
- Previous symbol:
- -
- Synonyms:
- NESH, SSH3BP3
- Chromosome:
- 17q21.32
- Locus Type:
- gene with protein product
- Date approved:
- 2004-03-11
- Date modifiied:
- 2016-10-05
Related products to: ABI3
Related articles to: ABI3
- Elucidating the molecular mechanisms that govern seed dormancy is important for developing crops with improved resistance to preharvest sprouting (PHS). A series of seed dormancy genes have been cloned, but the connections among different seed dormancy genes remain poorly understood. Here, we have revealed the relationship between two important dormancy quantitative trait loci (QTLs): SDR3.1 and Sdr4. SDR3.1 formed complexes with ABI3 and ABI5 and suppressed their activation of Sdr4 transcription. Haplotype analysis showed that the germination rate of SDR3.1 L-type and Sdr4 n- or K-type combinations was low, and the parents of modern core breeding do not contain l-type. Analysis of transgenic plants confirmed that orthologs of SDR3.1 have conserved functions in controlling seed dormancy in rice (Oryza sativa L.), foxtail millet (Setaria italica (L.) P. Beauv.), and maize (Zea mays), but they have different molecular regulatory mechanisms. This study uncovers the OsSDR3.1-ABI3/ABI5-Sdr4 regulatory module conferring improved PHS resistance, while establishing an effective approach to characterize core functional genes for important agronomic traits across Poaceae species with rice as a model. - Source: PubMed
Guo NaihuiAn RuihuXu MengxueLi YuanyuanRen ZongliangJiang JunCai BonianHuang XinzhuHu ShikaiShao GaonengJiao GuiaiXie LihongWang LingZhao FengliZhu YujunTang ShaoqingSheng ZhonghuaHu Peisong - A major bottleneck in genome editing of many perennial plants is their recalcitrance to transformation and regeneration. To boost genome editing in such perennial crops, transcriptional reprogramming of morphogenic genes is introduced by CRISPR-Combo, a versatile system for simultaneous genome editing and transcriptional activation in plant cells. In potato, we screen 17 morphogenic genes and identify 4 genes (WOX11/12, ARF5, ABI3-1, and ABI3-2) that promote regeneration of genome-edited hairy roots, and 3 of the 4 genes are also found to boost shoot regeneration by Agrobacterium-mediated stable transformation. Similarly, screening of 10 morphogenic genes in citrus leads to the identification of 5 genes (BBM3, FUS3, IPT1, SERK1, and STM) that enhance plant regeneration upon activation. In wild strawberry, we demonstrate that simultaneous activation of Baby Boom genes (BBM1 and BBM2) or of GRF3 and GIF1 reduces the generation time of genome-edited plants by over one month. Moreover, in poplar, we show that simultaneous activation of WUS and WOX11 synergistically promotes plant regeneration without exogenous plant hormones, which leads to a protocol of generating genome-edited poplar shoots in less than one month. Collectively, this study provides efficient strategies for boosting genome editing in four perennial crops. - Source: PubMed
Publication date: 2026/08/05
Ramasamy ManikandanLi GenGuo LeiFang HongEid AymanMandlik RushilCheng YanhaoNiedz Randall PCulver James NColeman Gary DLiu ZhongchiMandadi Kranthi KQi Yiping - Although the ABI3 S209F variant is a recognized genetic risk for Alzheimer's disease (AD), its pathogenic mechanism remains elusive. - Source: PubMed
Li ShengnanLu JiongtongZeng KaixingLu XingyuZhang JiahaoFeng SifanLiang ChunmeiCai YujieYao ShiHuang QingLiang GuocongChen RuiLi LiMa FubinXing JiaweiOuyang ChaoyueLuo LvWang JiayingLi YouHe ShengboZhao YuanyuanWang YanCui Lili - Retention mechanisms of abiraterone (Abi, Abi1) and its metabolites [Δ-Abi (D4A, Ab2), 3-keto-5α-Abi (Abi3), 3β-OH-5α-Abi (Abi4), 3α-OH-5α-Abi (Abi5), 3-keto-5β-Abi (Abi6), 3β-OH-5β-Abi (Abi7), 3α-OH-5β-Abi (Abi8) and 3α-OH-Abi (Abi9) on monomeric and polymeric ODS stationary phases were investigated using computational chemistry. Abi1/Abi9, Abi4/Abi5, Abi7/Abi8 and Abi3/Abi6 are pairs of diastereomers. The 1,3-diaxial interactions involving the C3‑hydroxy groups in Abi9, Abi5 and Abi8 appear to hinder hydration, leading to less favorable solvation and greater hydrophobicity than their corresponding diastereomers. Therefore, on monomeric ODS stationary phases, the elution orders were Abi1 < Abi9, Abi4 < Abi5, Abi7 < Abi8 and Abi3 ≈ Abi6, in agreement with the corresponding order of hydrophobicity. In contrast, on polymeric ODS stationary phases, the elution orders were Abi9 < Abi1, Abi5 < Abi4, Abi8 < Abi7 and Abi6 < Abi3. This reversal is likely attributable to the planarity recognition capability of the polymeric ODS stationary phase. On monomeric ODS stationary phases, the van der Waals interaction energies between Abi and its eight metabolites (Abi2 - Abi9) and the monomeric C12 stationary phase, calculated using the MM2 force field, showed a good correlation with their log k values. Furthermore, for six compounds bearing a C3‑hydroxyl group (Abi1/Abi9, Abi4/Abi5 and Abi7/Abi8), the hydration free energies calculated by the DFT/SMD method also showed a good correlation with their log k values. - Source: PubMed
Publication date: 2026/09/12
Haginaka JunHonda ChieHoriyama ShizuyoHayama NoboruHanai Toshihiko - Autophagy, a conserved intracellular recycling pathway, operates both non-selectively and through targeted degradation. In this study, we assess its role in Arabidopsis thaliana seed biology by examining loss-of-function mutants of ATG5 and ATG7 and their interaction with ABA signaling. Both atg5 and atg7 seeds display delayed germination relative to Col-0, an effect that is exacerbated by ABA. Histochemical staining reveals altered organization of lipid droplet and protein storage vacuole (PSV) organization in the mutants, and ATG8 fail to localize to PSVs when autophagy is impaired. Transcriptome profiling of atg7 seeds particularly under ABA treatment reveals substantial shifts in gene expression, with approximately 22 % of ABA-responsive differentially expressed genes. In wild-type seeds, ABI5 protein levels decline after imbibition; this process is delayed in atg mutants, which also accumulate higher levels of the ABI5 homolog bZIP67. Yeast two-hybrid (Y2H) and co-immunoprecipitation assays support a functional association between ATG8 and ABI3/ABI5 transcription factors, direct or indirect, consistent with a link between autophagy and ABA signaling. Collectively, our data support a role for autophagy in reserve mobilization during seed germination and suggest that autophagy contributes to the control of transcriptional networks associated with ABA responses. - Source: PubMed
Publication date: 2026/09/17
Contreras EstefaníaSánchez-Vicente InmaculadaPastor-Mora ElenaAylón-Rodríguez MarCeballos Mar GDelgado-Gutiérrez Miguel ÁngelLorenzo ÓscarVicente-Carbajosa JesúsIglesias-Fernández Raquel