ABCA13
- Known as:
- ABCA13
- Catalog number:
- 000895A
- Product Quantity:
- 250ul
- Category:
- -
- Supplier:
- ABM
- Gene target:
- ABCA13
Related genes to: ABCA13
- Gene:
- ABCA13 NIH gene
- Name:
- ATP binding cassette subfamily A member 13
- Previous symbol:
- -
- Synonyms:
- FLJ33876, FLJ33951
- Chromosome:
- 7p12.3
- Locus Type:
- gene with protein product
- Date approved:
- 2004-12-21
- Date modifiied:
- 2015-11-13
Related products to: ABCA13
Related articles to: ABCA13
- Chemotherapy resistance and disease progression remain major causes of mortality in osteosarcoma (OS). The miR-16 family is linked to tumors, but the specific function and treatment potential of the miR-16-1-3p passenger strand in OS remain unclear. - Source: PubMed
Publication date: 2026/06/26
Xue WenyuWang YuzhePugacheva PolinaSmirnova Anna VChuprov-Netochin RomanPustovalova MargaritaKuzmin Denis VLeonov Sergey - Pathogenic variants of can increase mutational load within colorectal cells, which may drive initiation and progression of colorectal cancer (CRC). We identified several variants within among CRCs from African Americans (AA). To predict and assess the functional significance of these variants, we employed a combination of in silico analyses and in vitro functionality assays. Our objective was to elucidate the correlation between computational predictions and functional outcomes. - Source: PubMed
Publication date: 2026/06/04
Rashid MudasirBrim HassanTeng ShaoleiSobitan AdebiyiCruz-Cosme RuthQiyi TangKoi MinoruCasazza KatherineSurtees Jennifer ACarethers John MAshktorab Hassan - The clinical utility of integrated proteogenomic biomarkers for predicting chemotherapy response in triple-negative breast cancer remains underexplored. We prospectively analyzed paired baseline and post-treatment tumor samples from 50 patients with stage II-III TNBC treated with anthracycline- and taxane-based neoadjuvant chemotherapy, integrating whole-exome sequencing, RNA sequencing, global proteomics, and phosphoproteomics. - Source: PubMed
Publication date: 2026/04/14
Lee Dong KiKim Min HwanHwang YumiKim Seul-GiRyu Won-JiKim Geon-UkYun Hyun MyoungPark ShinyoungLee Jeong DongHan Hyun JuKim Gun MinKim Kyung-HeePark Jong BaeKim Min JungKoo Ja SeungKim Jee YePark Hyung SeokKim Seung IlGee Heon YungPark SehoSohn Joohyuk - Severe burns are a major global health concern, and are associated with long-term physical and psychological impairments, multi-organ dysfunction, and substantial morbidity and mortality. While burn injuries in adults trigger systemic immuno-metabolic alterations-characterized by white adipose tissue browning, elevated resting energy expenditure, widespread catabolism, and inflammation-these adaptive responses are considerably impaired in older adults, with molecular mechanisms behind these differences remaining largely unclear. As a key regulator of systemic metabolism, investigating the pathological role of adipose tissue (AT) postburn may reveal novel targets that could potentially improve patient outcomes. In this study, we conducted bulk mRNA sequencing and analysis of AT from adult and aged mice to elucidate the transcriptomic changes underlying the distinct postburn responses in these populations. After examining differentially expressed genes in the adult and aged burn mice, the top six upregulated genes in adults (Ucp1, Lgr6, Dio2, Lncbate10, Fabp3, Kng2) were primarily associated with thermogenesis, whereas those in the aged mice (Car6, Spata25, Gm128, Btbd16, Lipm, Abca13) were linked to inflammation, tissue repair, and lipid metabolism. Furthermore, our gene co-expression and enrichment map analysis identified burn-associated modules related to fatty acid oxidation, acetyl thioester CoA, and thermogenesis in adults, whereas leukocyte migration, tumor necrosis factor production, and sister chromatids were in aged mice. Notably, Ppara and Sfpi1 emerged as potential master regulators of co-expressed genes in burn AT of adult and aged mice, respectively. Our findings highlight age-specific differences in burn-induced AT responses and uncover potential molecular regulators that may inform targeted therapeutic strategies to mitigate the post-burn stress response. - Source: PubMed
Bhattachan PunitVlavcheski FilipWojtowicz-Piotrowski StephanieJeschke Marc G - This systematic review explores the hypothesis that various lipid categories and lipid metabolism-related genomic variations link to mental disorders, seeking potential clinically useful markers. - Source: PubMed
Publication date: 2025/03/11
Modesti Martina NicoleArena Jan FrancescoDel Casale AntonioGentile GiovannaBorro MarinaParmigiani GiovannaSimmaco MaurizioGuariglia CeciliaFerracuti Stefano