CD95 _ FAS
- Known as:
- CD95 _ Fas Cell Surface Death Receptor
- Catalog number:
- MC103
- Product Quantity:
- 100 Tests
- Category:
- -
- Supplier:
- ACR
- Gene target:
- CD95 _ FAS
Related genes to: CD95 _ FAS
- Gene:
- FAS NIH gene
- Name:
- Fas cell surface death receptor
- Previous symbol:
- FAS1, APT1, TNFRSF6
- Synonyms:
- CD95, APO-1
- Chromosome:
- 10q23.31
- Locus Type:
- gene with protein product
- Date approved:
- 1992-06-25
- Date modifiied:
- 2019-04-23
Related products to: CD95 _ FAS
Related articles to: CD95 _ FAS
- Lateral ankle instability is a common problem with substantial morbidity in both the athletic and general population. Guidelines for use of ligament augmentation devices continue to be developed. The below is a case describing surgical treatment of ankle instability using TEKBRACE (TheraMicro, LLC), a new ligament augmentation scaffold, for the anterior talofibular ligament in a patient at high risk of failure.Level of Evidence:Level V. - Source: PubMed
Publication date: 2026/08/12
Pitts Charles C - Foot and ankle injuries are among the most common musculoskeletal conditions encountered in both athletic and general populations, accounting for a substantial proportion of emergency and sports medicine visits. These injuries encompass a wide spectrum, from acute ligamentous sprains to more subtle and frequently misdiagnosed conditions such as Lisfranc ligament injuries, tarsal coalitions, and posterior tibial tendon dislocations. The complex anatomy and biomechanics of the foot and ankle, combined with the high functional demands placed upon them during gait and athletic activity, underscore the importance of accurate diagnosis and appropriate management. This article reviews the relevant anatomy of the foot and ankle, discusses common and clinically significant injuries, and highlights key aspects of diagnosis, imaging, and treatment. Both nonoperative and operative treatment strategies are addressed, with consideration given to injury severity, stability, and patient-specific factors. Finally, the importance of rehabilitation and injury prevention in reducing recurrence and optimizing long-term outcomes is discussed. - Source: PubMed
Publication date: 2026/08/12
Rivenburgh Dennis - To assess whether a 20-min power nap reduces fatigue and daytime sleepiness among emergency doctors following night shifts. - Source: PubMed
Publication date: 2026/07/09
Hussin Wan Noorulfaten Azreen WanJaafar Mohd JoharTan Hui JanIsa Mohd Hisham MohdSahibulddin Siti ZalehaKhaili Nur Arifah MohdSaiboon Ismail Mohd - Cortical organoids (COs) represent a powerful model system that recapitulates key aspects of human brain development, enabling the study of neurodevelopmental processes, cellular diversity, and disease mechanisms in a physiologically relevant 3D environment. However, traditional histological analysis of COs relies on tissue sectioning, which limits the ability to capture the full spatial complexity of organoid architecture. In this study, we establish a framework for applying CLARI-O, an improved tissue-clearing technique, for intact COs and organoid-based systems, enabling comprehensive 3D visualization and analysis of 3D organizational features. Using CLARI-O in combination with high-resolution imaging, we demonstrate the utility of tissue clearing for studying glial populations, including oligodendrocytes and microglia, considered to be underrepresented in COs, and their interactions with neurons. Additionally, we apply this method to forebrain assembloids (FAs) to visualize cellular heterogeneity and the interface between ventral and dorsal regions. Finally, we use CLARI-O to study mouse brains containing xenotransplanted COs (MB-COs) to evaluate human cell integration, migration, vascularization, and structural connectivity. This is the first study to demonstrate how tissue clearing can be used after functional assays such as calcium imaging to correlate neural activity with structural analysis in MB-COs. Together, this work establishes CLARI-O as a powerful tool for advancing 3D structural and functional interrogation of human CO-derived systems, enhancing their value for disease modeling, drug screening, and translational neuroscience. - Source: PubMed
Publication date: 2026/07/28
Beyene SamraThunemann MartinCampbell Natalie BakerKharitonova Elizabeth KKlorfeld-Auslender ShiraMortazavi FarzadZeldich Ella - Obesity is associated with the enrichment of unsaturated triacylglycerol (TAG) species in adipose tissue, but the mechanism driving this selective lipid accumulation remains unclear. We investigated whether substrate-selective lipolysis contributes to the retention of unsaturated fatty acids (FAs) in obese adipose tissue. Lipidomic profiling revealed predominant enrichment of FA 18:1 and FA 18:2 in midlife-predominant obese adipose TAGs, and functional assays showed that adipose triglyceride lipase preferentially hydrolyzes saturated TAGs under conditions of sufficient substrate supply. These results identify lipase substrate selectivity as a mechanistic contributor to lipid remodeling in obesity and a potential target for modulating adipose lipid turnover. - Source: PubMed
Publication date: 2026/08/11
Sheng JiantingQi ShaohuaChan MichaelWang ElaineHan XianlinHsueh Willa AYang LiWong Stephen T C