ADAM15 _ MDC15 Antibody (Antigen Affinity Purified)
- Known as:
- ADAM15 _ MDC15 Antibody (Antigen Affinity Purified)
- Catalog number:
- 10517-RP01
- Product Quantity:
- 100
- Category:
- -
- Supplier:
- Smart Serology
- Gene target:
- ADAM15 _ MDC15 Antibody (Antigen Affinity Purified)
Related genes to: ADAM15 _ MDC15 Antibody (Antigen Affinity Purified)
- Gene:
- ADAM15 NIH gene
- Name:
- ADAM metallopeptidase domain 15
- Previous symbol:
- -
- Synonyms:
- MDC15
- Chromosome:
- 1q21.3
- Locus Type:
- gene with protein product
- Date approved:
- 1998-12-01
- Date modifiied:
- 2015-08-24
Related products to: ADAM15 _ MDC15 Antibody (Antigen Affinity Purified)
Related articles to: ADAM15 _ MDC15 Antibody (Antigen Affinity Purified)
- Approximately 10% of glioblastomas harbor targetable genomic fusions. participates in a variety of fusion events that drive tumorigenesis. Two previous reports have described fusions in adult glioblastoma patients with poor survival. - Source: PubMed
Publication date: 2026/08/20
Sadanandappa Madhumala KKarbhari NishikaKnowles BrizhaPalisoul Scott MHughes Edward GTafe Laura JZanazzi George JLin Chun-ChiehHong Jennifer - Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, with significant associated morbidity and mortality. The pathophysiology underlying AF is complex, and this has limited the development of effective therapies. ADAMs (a disintegrin and metalloproteinase) are transmembrane proteinases with diverse functions involving cell-cell communication and extracellular matrix homeostasis. ADAM15 specifically has been implicated in AF pathogenesis in large-scale genetic association studies. Given the importance of atrial remodelling in AF pathogenesis, we sought to ascertain the effect of ADAM15 deficiency in murine atrial biology. - Source: PubMed
Bapat AneeshClauss SebastianXiao LingJameson HeatherRetournard AnthonyHanley AlanEllinor Patrick T - Identifying new drug targets is essential for improving breast cancer survival. The proteome provides a rich source for potential therapeutic targets. This study aimed to identify protein markers and therapeutic targets for breast cancer by using proteome-wide Mendelian randomization (MR). - Source: PubMed
Publication date: 2025/08/04
Cao ZheXuPeng QiyunTan Shenglan - Aqueous humor outflow through the trabecular meshwork (TM) is segmental, demonstrating high flow (HF) and low flow (LF) regions. Here, we investigate transcriptomic differences between flow regions in naïve mouse and non-glaucomatous human TM tissue to better understand intraocular pressure (IOP) regulation. - Source: PubMed
Publication date: 2026/07/24
Wong Cydney ARead A ThomasChrenek MicahLi GuorongStamer W DanielWood Levi BEthier C Ross - A disintegrin and metalloproteinase 15 (ADAM15) is a cell-surface protease with a paradoxical role in cancer development. In this review, we provide a comprehensive overview of the dual functions of ADAM15, highlighting recent mechanisms including exosomal communication, non-coding (nc)RNA regulation (miR-3174, miR-526b-5p, and lncRNA NCK1-AS1), and antiangiogenic metargidin peptide (AMEP), which has completed Phase I trials. We also present a systematic therapeutic strategy matrix covering small molecules, antibodies, RNA therapeutics, proteolysis-targeting chimeras (PROTACs), G-quadruplex stabilizers, and combination therapies, alongside a detailed research gap analysis and actionable future directions. - Source: PubMed
Publication date: 2026/07/21
El-Far AliSong BinghuiFu JunjiangCheng Jingliang