PRLR _ Prolactin receptor Antibody
- Known as:
- PRLR _ Prolactin receptor Antibody
- Catalog number:
- 10278-RP02
- Product Quantity:
- 200
- Category:
- -
- Supplier:
- Smart Serology
- Gene target:
- PRLR _ Prolactin receptor Antibody
Related genes to: PRLR _ Prolactin receptor Antibody
- Gene:
- PRLR NIH gene
- Name:
- prolactin receptor
- Previous symbol:
- -
- Synonyms:
- -
- Chromosome:
- 5p13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1989-12-01
- Date modifiied:
- 2016-10-05
Related products to: PRLR _ Prolactin receptor Antibody
Related articles to: PRLR _ Prolactin receptor Antibody
- Non-functioning pituitary adenoma (NFPA) is the most common pituitary tumor. Due to the lack of hormone hypersecretion, it is often diagnosed when the tumor enlarges and gives compression symptoms. Surgical resection is the primary treatment modality; however, complete remission rates remain suboptimal. In this study, we aimed to investigate differentially expressed genes (DEGs) that may be involved in NFPA pathogenesis. - Source: PubMed
Uzkul Nisa DevrimAkkoyunlu Deniz SunnetciCabuk BurakIsik Elif BusraIskenderoglu Elmas TunaKeskin Seda ErenCine NaciSavli Hakan - To elucidate the central mechanism of pituitary-derived prolactin (PRL) in hepatic lipid homeostasis and identify therapeutic targets for metabolic dysfunction-associated fatty liver disease (MASLD). - Source: PubMed
Publication date: 2026/06/03
Zhu YeWu KexinWu TianyuFang DaZhang PengziWang JinBi Yan - Hyperprolactinemia is commonly caused by pituitary prolactinomas or medications and is typically managed with dopamine agonists (DAs). However, ectopic prolactin secretion from non-pituitary sources is rare and often unresponsive to medical therapy. Disseminated peritoneal leiomyomatosis (DPL), a benign condition characterized by diffuse intra-abdominal smooth muscle nodules, has not been previously reported as a source of ectopic prolactin production. The pathogenesis of DPL remains unclear, and no standardized treatment exists. Here we report a rare case of hyperprolactinemia in a female patient caused by DPL, who was successfully managed by surgical resection and postoperative leuprorelin therapy. - Source: PubMed
Publication date: 2025/12/19
Liu ZilingShen YangmeiHe Xiang - Heat stress (HS) is among the most economically consequential environmental challenges to global dairy production, causing progressive declines in milk yield, compositional quality, and mammary cellular integrity. The temperature-humidity index (THI) is the primary thermal load metric, with performance-impairment thresholds typically beginning at THI 68 in Holstein cattle, with severe impacts manifesting beyond THI 72; breed-specific thresholds for Jersey, Brown Swiss, and Simmental cows differ owing to their lower metabolic heat load and greater inherent thermotolerance. At the molecular level, HS activates heat shock protein networks-notably , , and -through / transcriptional activation, while simultaneously suppressing casein genes (, , ), lipogenic genes (, , ), amino acid transporters (, ), and mTOR-AKT-STAT5 translational machinery, collectively impairing milk biosynthetic capacity. Pro-apoptotic signaling (, upregulation; downregulation) and mitochondrial dysfunction further compromise mammary epithelial viability. Post-transcriptional regulation through miRNA, circRNA, and lncRNA competing endogenous RNA networks, alongside epitranscriptomic m6A modifications, adds further regulatory complexity. Genome-wide association studies have identified SNPs in , , , and as thermotolerance candidates compatible with sustained milk production. Nutritional supplementation with methionine, arginine, and taurine partially restores cellular synthetic capacity. Integrating multi-trait genomic selection with introgression, precision cooling, and targeted nutrition offers the most viable path toward climate-resilient, high-producing dairy cattle. - Source: PubMed
Publication date: 2026/05/21
Ma QingshanTharwat MohamedAlshanbari Fahad AKhan Muhammad Zahoor - Wilms tumor presents a heterogeneous tumor microenvironment. This study aimed to characterize the tumor microenvironment and identify prognostic genes to improve therapeutic strategies. - Source: PubMed
Publication date: 2026/05/20
Gao ZhiqiangLin JieTang HuafeiLi AoLi RuiXu AoHu RuiXu ShuaiZhang MaolinYang WenmingHuang HaijingZhang ZhengLiu Feng