CD146 _ MCAM Antibody
- Known as:
- CD146 _ MCAM Antibody
- Catalog number:
- 10115-RP01
- Product Quantity:
- 200
- Category:
- -
- Supplier:
- Smart Serology
- Gene target:
- CD146 _ MCAM Antibody
Related genes to: CD146 _ MCAM Antibody
- Gene:
- MCAM NIH gene
- Name:
- melanoma cell adhesion molecule
- Previous symbol:
- -
- Synonyms:
- MUC18, CD146, MelCAM, METCAM, HEMCAM
- Chromosome:
- 11q23.3
- Locus Type:
- gene with protein product
- Date approved:
- 1995-12-18
- Date modifiied:
- 2019-04-16
Related products to: CD146 _ MCAM Antibody
Related articles to: CD146 _ MCAM Antibody
- Dental-derived mesenchymal stem cells show considerable variability in their differentiation potential due to the use of nonspecific surface markers and technical limitations in isolation protocols. This study aimed to employ single-cell RNA sequencing to compare the cellular composition of cultured stem cells from apical papilla (SCAPs) and dental pulp (DPSCs), with the goal of detecting subpopulations underlying their divergent regenerative behaviour and identifying markers that can facilitate future isolation and functional targeting. - Source: PubMed
Publication date: 2026/05/05
Shah Maanas SSayegh Mohamed AlKhalil Mennatullah MSundarabupathi ManoAlKhnbashi OmerSamaranayake LakshmanKhyriem CosterwellSultana MeharEgusa HiroshiJamal Mohamed - The pulmonary vasculature develops in close association with the airways and this network expands through the interactions between endothelial cells and the surrounding mesenchymal cells, the pericytes. Emerging evidence suggests that pericytes play a significant role in various lung diseases, such as congenital diaphragmatic hernia and chronic obstructive pulmonary disease. However, characterizing pericytes remains challenging, impeding our understanding of their exact role in lung development and disease. Therefore, we used a novel cell tracing technology based on a bacterial DNA cytosine methyltransferase (Dcm) fused to RNA polymerase II (DCM-TM) to methylate active genes. The doxycycline inducible Dcm-PolII fusion protein was activated at specific time points during gestation, while the epigenetically labeled genes were analyzed at later time points. This retrospective cell tracing was coupled to single-cell RNA sequencing to track the development of mouse pulmonary pericytes at the single cell level. This revealed the paths to differentiation of perivascular progenitors into pericytes and vascular smooth muscle cells. Temporal analysis uncovered dynamic gene expression profiles during pericyte differentiation, highlighting pathways crucial for pulmonary vascular development. Further analysis showed intricate signaling interactions between pericyte progenitors and mature pericytes, and we validated MCAM as a bona fide pulmonary pericyte marker. Our findings challenge conventional views on pericyte origin and underscore the importance of accurate pericyte identification in developmental and disease contexts. Overall, this study enhances our understanding of pulmonary pericyte ontogeny and differentiation, offering insights into their potential as therapeutic targets in pericyte-associated lung diseases. - Source: PubMed
Publication date: 2026/04/22
Sreeram Isabel ITan BeatriceBoers Ruben GBoers Joachim BBoerema-De Munck AnneBuscop-Van Kempen MarjonVan Ijcken Wilfred F JSchnater J MarcoWijnen René M HGribnau JoostRottier Robbert J - Alloantigen H is one of thirteen systems in the chicken. Little is known about this system which has two serological alleles. The objectives of this study were (1) to identify the genetic region encoding the chicken alloantigen H, and (2) to develop DNA detection-based methods to aid H system allele identification. - Source: PubMed
Publication date: 2026/03/31
Fulton Janet EMcCarron Amy MWolc AnnaSparling Brandi AAli LowdanJaeger CourtneyTaylor Robert L - We present an epi-illumination multi-camera array microscope (epi-MCAM) designed for wide-field reflective imaging of non-transparent samples. The epi-MCAM contains 24 tightly packed and synchronized epi-illumination microscope units, arranged in a 4 × 6 planar array at 18 mm spacing. Each unit contains a unique CMOS image sensor (13 megapixels each), an objective and tube lens pair, and a beamsplitter and epi-illumination light path. An epi-MCAM capture cycle produces a stitched image covering 72 × 108 mm at a micrometer scale resolution down to 2.46 m. To image samples exceeding this native field of view, we translate the entire array across the sample surface to enable high-resolution coverage of large objects. We demonstrate the system's ability to image both flat and three-dimensionally structured reflective samples, such as semiconductor wafers and printed circuit boards, which highlight the epi-MCAM's strong potential within industrial inspection applications. - Source: PubMed
Bao XiangjiangKreiss LucasCook Clare BGong HaoyuHarfouche MarkHorstmeyer Roarke - The present study evaluated the decolourisation capacity of four native fungal strains on synthetic dyes and assessed the biotechnological potential of the selected strains in the decolourisation of a real industrial effluent. Discolouration assays were performed on solid medium using six dyes, and the production profiles of laccase, lignin peroxidase, and manganese peroxidase were determined in liquid cultures. Laccase was the most abundantly produced enzyme in all strains. Based on decolourisation potential and enzymatic production curves, Trametes maxima CU1 and Trametes hirsuta CS5 were selected. Eighteen-day-old culture supernatants were used for the decolourisation of Reactive Blue 19 (RB19), Reactive Black 5 (RB5), Crystal Voilet (CV), and the industrial effluent. T. maxima CU1 showed the highest discolouration percentages of synthetic dyes, reaching 97% in AR19 and 61% in RB5 at six hours, while CS5 required nine hours for 41% and 25%, respectively. For CV, CU1 reached 50% at 48 h, and CS5 only 6%. In the industrial effluent, CS5 achieved > 50% discolouration at 293 nm at six hours. CU1 and T. versicolor UAMH 8272 reached 21% and 17%, respectively. At 613 nm, CU1 showed the highest activity (60% at six hours). The process consumed 10,869.43 MJ, the electricity accounting for 76.13% of total energy use. These results confirm T. maxima CU1 high efficiency, highlighting the need to optimize energy consumption for sustainable applications. - Source: PubMed
Publication date: 2026/04/27
López-Sandin IosvanyGonzález-Urbina ÁngelesGutiérrez-Soto GuadalupeIqbal Hafiz M NLevin LauraVillareal-Chiu Juan FranciscoGarcía-Gómez CelestinoChávez-Montes AbelardoElizondo-Luevano Joel HoracioCastillo-Velázquez UzielHernández-Vidal GustavoThakur AmanParra-Saldivar Roberto