CD158a _ KIR2DL1
- Known as:
- CD158a _ KIR2DL1
- Catalog number:
- GTX76000
- Product Quantity:
- 200 µg
- Category:
- -
- Supplier:
- ACR
- Gene target:
- CD158a _ KIR2DL1
Related genes to: CD158a _ KIR2DL1
- Gene:
- KIR2DL1 NIH gene
- Name:
- killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
- Previous symbol:
- -
- Synonyms:
- cl-42, nkat1, 47.11, p58.1, CD158A
- Chromosome:
- 19q13.42
- Locus Type:
- gene with protein product
- Date approved:
- 1997-11-14
- Date modifiied:
- 2016-11-09
Related products to: CD158a _ KIR2DL1
Related articles to: CD158a _ KIR2DL1
- Trauma induces significant physiological changes that can lead to substantial morbidity and mortality. Many of these changes alter immune homeostasis, which underlies seemingly disparate syndromes of systemic inflammation and global immune suppression, the causes of which remain unclear. Innate immune cells play a key role in the response to trauma, and recent studies have suggested that natural killer (NK) cells are dynamically responsive to mild versus severe systemic trauma. - Source: PubMed
Publication date: 2026/08/10
Bazzi NaghamStempora LindaHensman HannahQuinones Patricia MartinezNegron Isabel RodriguezKrynychka KaterynaGelbard Rondi BGrey Scott FSchobel Seth AElster EricFernandez-Moure JosephKirk Allan D - Reproductive failures, including recurrent implantation failures (RIF), recurrent pregnancy losses (RPL), and adverse pregnancy outcomes (APO), are increasingly linked to immunological factors at the maternalfetal interface. Killer immunoglobulin-like receptors (KIRs) on natural killer (NK) cells play a key role in regulating maternal immune responses to trophoblast HLA-C antigens. - Source: PubMed
Kovarova TerezaBitoova MartinaLuxova StepankaKoudova MonikaKoucky MichalCerna Karin - The killer-cell immunoglobulin-like receptors (KIR) are a family of activating and inhibitory Class I human leukocyte antigen (HLA-I) binding receptors expressed on natural killer (NK) cells and subsets of T cells. The KIR detect HLA-I molecules in a peptide-dependent manner, with some KIR displaying exquisite peptide specificity. Studying peptide recognition by KIR often uses TAP-deficient cell lines expressing single HLA-I alleles, which are heterogenous and time consuming to generate. Here, we established an alternative approach using peptide-exchange technologies hitherto developed for studying T cell recognition of HLA-I. - Source: PubMed
Publication date: 2026/05/25
Murali Tanusya MLi BeiningHoos EmeryCollinson LucyLong Eric ODushek OmerElliott TimSim Malcolm J W - Immune dysregulation and cognitive deficits are increasingly recognized in adolescent major depressive disorder (MDD), yet their interrelationship remains unclear. This study aimed to investigate peripheral immune-inflammatory alterations and natural killer (NK) cell phenotypes, and explore their association with cognitive function in adolescent MDD. - Source: PubMed
Publication date: 2026/05/16
Wang JiahuiHou LingzhiLi CaiLiu YitongXu YanHe YangYang LeiWang LiLiu QidongCheng JunZhang YanyanMa YunmiaoXu HaiweiLi Hong - The Novel KIR3DL1*0010123, KIR3DL1*0010124, KIR2DL1*0010108, KIR2DL1*0010109 alleles were identified in healthy individuals from the Indian Population. - Source: PubMed
Sharma GauravAgarwal DishaKhadwal AlkaDas ReenaMalhotra Pankaj