SH2D3C Antibody (monoclonal) (M01)
- Known as:
- SH2D3C Antibody (mab) (M01)
- Catalog number:
- AT3863a
- Product Quantity:
- 0.1mg
- Category:
- -
- Supplier:
- Abgen
- Gene target:
- SH2D3C Antibody (monoclonal) (M01)
Related genes to: SH2D3C Antibody (monoclonal) (M01)
- Gene:
- GTF2H2B NIH gene
- Name:
- general transcription factor IIH subunit 2B (pseudogene)
- Previous symbol:
- -
- Synonyms:
- DKFZP686M0199
- Chromosome:
- 5q13.2
- Locus Type:
- pseudogene
- Date approved:
- 2008-07-04
- Date modifiied:
- 2015-11-09
- Gene:
- POLR1A NIH gene
- Name:
- RNA polymerase I subunit A
- Previous symbol:
- -
- Synonyms:
- DKFZP586M0122, FLJ21915, RPO1-4, RPA1
- Chromosome:
- 2p11.2
- Locus Type:
- gene with protein product
- Date approved:
- 2003-04-01
- Date modifiied:
- 2017-06-28
- Gene:
- SH2D3C NIH gene
- Name:
- SH2 domain containing 3C
- Previous symbol:
- -
- Synonyms:
- NSP3
- Chromosome:
- 9q34.11
- Locus Type:
- gene with protein product
- Date approved:
- 2001-11-19
- Date modifiied:
- 2016-10-05
- Gene:
- TDRP NIH gene
- Name:
- testis development related protein
- Previous symbol:
- C8orf42
- Synonyms:
- INM01, TDRP1, TDRP2
- Chromosome:
- 8p23.3
- Locus Type:
- gene with protein product
- Date approved:
- 2005-07-28
- Date modifiied:
- 2015-08-26
Related products to: SH2D3C Antibody (monoclonal) (M01)
Related articles to: SH2D3C Antibody (monoclonal) (M01)
- Acquired aplastic anemia (AA) is an immune-mediated bone marrow failure syndrome characterized by destruction of hematopoietic stem and progenitor cells (HSPCs). Although HLA class II alleles are consistently associated with disease susceptibility, the candidate self-peptides presented by these molecules remain largely unknown. - Source: PubMed
Publication date: 2026/09/08
Correa Lara MaximilianoGarcía Chavez JaimeMartinez Hernandez Erika - Geese are key domesticated waterfowl in Asia, where annual egg number and laying duration influence economic value. To investigate the genomic basis of laying seasonality, we generated whole-genome resequencing data for 314 geese from six Chinese breeds and focused on three with contrasting reproductive schedules: low-latitude Ding'an geese, which have a prolonged laying period with moderate annual egg yield, and high-latitude Huoyan and Zi geese, which show short, highly seasonal laying but high egg production. By integrating Fst, GWAS and haplotype-based statistics, we identified 16 candidate genes, including reproduction-related loci (AGTR2, IARS, PCGF6) and retinal genes (FRMD4B, PROS1, SH2D3C, ZEB2). Genomic regions surrounding PCGF6 and PROS1 showed clear signatures of selection, with reduced nucleotide diversity and strongly differentiated haplotypes between latitude-defined groups. Multiple downstream and 3' untranslated-region SNPs at these loci exhibited large allele-frequency shifts and are predicted to alter transcriptional regulation, suggesting a link between retinal photoreception, photoperiodic or circadian signaling and the timing and duration of egg laying. These findings highlight the role of retinal pathways in goose reproductive seasonality and provide targets for genomic selection to potentially extend the laying period. - Source: PubMed
Publication date: 2026/03/24
Chen HaoMiao JunjieHu YimingZhou JingTan HongliLi JingMao HuirongOuyang JingHuang MinGu LihongYan Xueming - Hypertrophic cardiomyopathy (HCM) is a prevalent cardiovascular disorder affecting populations worldwide, characterized by abnormal thickening of the heart muscle.(Supporting S1) The development of HCM is influenced by multiple factors, including genetic mutations, geographical conditions, lifestyle, and environmental exposures. The availability of extensive genomic datasets in public repositories provides an opportunity to identify potential genetic contributors and functional biomarkers associated with HCM. Previous studies have highlighted the pivotal role of the MYBPC3 gene in the pathogenesis of HCM. In this study, computational analyses were performed to predict gene mutations and functional biomarkers using RNA-sequencing and whole exome sequencing datasets. A total of 12 RNA-sequencing samples, comprising four healthy controls and eight HCM cases, along with 12 exome sequencing datasets, were retrieved from the Gene Expression Omnibus (GEO) database. RNA-sequencing analysis identified the top 20 differentially expressed genes associated with HCM, including MIB2, ZBTB48, MYBPC3, PRPF40B, CD27-AS1, MYH7, WDR90, KDM8, BCAM, ZSWIM9, KANK3, CCDC85A, ZNF512B, POLR3H, NUP210, PSMG4, GPLD1, GNL1, SH2D3C, and COL4A6. Among these, MYH7 exhibited the highest expression level, showing strong similarity to MYBPC3 in its association with HCM. Whole exome sequencing analysis further identified a panel of variant genes including MYBPC3, MYH6, MYH7, TNT, Titin, Desmin, ACE1, TGF-beta, Ang-2, SGCG, SGCA, DMD, and LaminA/C, all previously implicated in HCM pathophysiology. This integrative study underscores the correlation between differential gene expression patterns and clinical variants in HCM, providing valuable insights into the molecular mechanisms underlying the disease. - Source: PubMed
Publication date: 2025/11/21
Cn PrashanthaR RamachandraNm GuruprasadReddy Vaddi Damodara - Sjögren's syndrome (SS) is an autoimmune disorder affecting exocrine glands, causing dry mouth and eyes, with no effective treatment. While high-throughput sequencing has provided insights into its mechanisms, the role of alternative splicing (AS) in SS remains underexplored. - Source: PubMed
Publication date: 2025/03/18
Chen JiaxuShi ZhenghaoXue Luan - In the original publication [...]. - Source: PubMed
Publication date: 2025/01/14
Yeh Yuan-ChiehLawal BashirHsiao MichaelHuang Tse-HungHuang Chi-Ying F