GTF2H1 Antibody (monoclonal) (M02)
- Known as:
- GTF2H1 Antibody (mab) (M02)
- Catalog number:
- AT2288a
- Product Quantity:
- 0.1mg
- Category:
- -
- Supplier:
- Abgen
- Gene target:
- GTF2H1 Antibody (monoclonal) (M02)
Related genes to: GTF2H1 Antibody (monoclonal) (M02)
- Gene:
- EMC10 NIH gene
- Name:
- ER membrane protein complex subunit 10
- Previous symbol:
- C19orf63
- Synonyms:
- INM02, HSS1, HSM1
- Chromosome:
- 19q13.33
- Locus Type:
- gene with protein product
- Date approved:
- 2007-07-17
- Date modifiied:
- 2016-12-01
- Gene:
- GTF2H1 NIH gene
- Name:
- general transcription factor IIH subunit 1
- Previous symbol:
- -
- Synonyms:
- BTF2, P62, TFIIH
- Chromosome:
- 11p15.1
- Locus Type:
- gene with protein product
- Date approved:
- 1993-08-16
- Date modifiied:
- 2016-10-05
- Gene:
- MRPL1 NIH gene
- Name:
- mitochondrial ribosomal protein L1
- Previous symbol:
- -
- Synonyms:
- BM022
- Chromosome:
- 4q21.1
- Locus Type:
- gene with protein product
- Date approved:
- 2001-02-28
- Date modifiied:
- 2015-08-25
- Gene:
- PMS2 NIH gene
- Name:
- PMS1 homolog 2, mismatch repair system component
- Previous symbol:
- PMSL2
- Synonyms:
- H_DJ0042M02.9, HNPCC4, MLH4
- Chromosome:
- 7p22.1
- Locus Type:
- gene with protein product
- Date approved:
- 1994-12-13
- Date modifiied:
- 2019-04-23
- Gene:
- SESN2 NIH gene
- Name:
- sestrin 2
- Previous symbol:
- -
- Synonyms:
- SES2, DKFZp761M0212, HI95, SEST2
- Chromosome:
- 1p35.3
- Locus Type:
- gene with protein product
- Date approved:
- 2003-09-03
- Date modifiied:
- 2016-10-05
Related products to: GTF2H1 Antibody (monoclonal) (M02)
Related articles to: GTF2H1 Antibody (monoclonal) (M02)
- Chronic Obstructive Pulmonary Disease (COPD) and Rheumatoid Arthritis (RA) are among the leading causes of illness and mortality globally. Many studies claim that these diseases are interconnected. However, the underlying molecular processes and shared biomarkers between RA and COPD are still undiscovered. - Source: PubMed
Publication date: 2026/07/27
Tasnim WahiaMondal M Rubaiyat Hossain - To identify rare and common copy number variants (CNVs) associated with strabismus and amblyopia. - Source: PubMed
Lee Kyoung A ViolaWhitman Mary C - Deficiency in DNA-damage repair (DDR) genes, often due to disruptive coding variants, is linked to higher cancer risk. Our previous study has revealed the association between rare loss-of-function variants in DDR genes and the risk of lung cancer. However, it is still challenging to study the predisposing role of rare regulatory variants of these genes. - Source: PubMed
Publication date: 2024/12/03
An MingxingChen CongcongXiang JunLi YangQiu PinyuTang YiruLiu XinyueGu YayunQin NaHe YuanlinZhu MengJiang YueDai JunchengJin GuangfuMa HongxiaWang ChengHu ZhibinShen Hongbing - Augmenter of liver regeneration (ALR) is believed to protect against acute kidney injury (AKI). The objective of this study was to investigate the mechanisms of ALR in the transition from AKI to chronic kidney disease (CKD). - Source: PubMed
Publication date: 2024/11/27
Wang ChunxiaZeng XujiaYang PengfeiWang GangZhang ZhengLiao Xiaohui - The fusion of autophagosomes and lysosomes is essential for the prevention of nonalcoholic fatty liver disease (NAFLD). Here, we generate a hepatocyte-specific CHIP knockout (H-KO) mouse model that develops NAFLD more rapidly in response to a high-fat diet (HFD) or high-fat, high-fructose diet (HFHFD). The accumulation of P62 and LC3 in the livers of H-KO mice and CHIP-depleted cells indicates the inhibition of autophagosome-lysosome fusion. AAV8-mediated overexpression of CHIP in the murine liver slows the progression of NAFLD induced by HFD or HFHFD feeding. Mechanistically, CHIP induced K63- and K27-linked polyubiquitination at the lysine 198 residue of STX17, resulting in increased STX17-SNAP29-VAMP8 complex formation. The STX17 K198R mutant was not ubiquitinated by CHIP; it interfered with its interaction with VAMP8, rendering STX17 incapable of inhibiting steatosis development in mice. These results indicate that a signaling regulatory mechanism involving CHIP-mediated non-degradative ubiquitination of STX17 is necessary for autophagosome-lysosome fusion. - Source: PubMed
Publication date: 2024/10/02
Rho HyunjinKim SeungyeonKim Seung UpKim Jeong WonLee Sang HoonPark Sang HoonEscorcia Freddy EChung Joon-YongSong Jaewhan