CD95 _ FAS
- Known as:
- CD95 _ Fas Cell Surface Death Receptor
- Catalog number:
- GTX13549
- Product Quantity:
- 50 µg
- Category:
- -
- Supplier:
- ACR
- Gene target:
- CD95 _ FAS
Related genes to: CD95 _ FAS
- Gene:
- FAS NIH gene
- Name:
- Fas cell surface death receptor
- Previous symbol:
- FAS1, APT1, TNFRSF6
- Synonyms:
- CD95, APO-1
- Chromosome:
- 10q23.31
- Locus Type:
- gene with protein product
- Date approved:
- 1992-06-25
- Date modifiied:
- 2019-04-23
Related products to: CD95 _ FAS
Related articles to: CD95 _ FAS
- This study aimed to evaluate the safety and effectiveness of two types of absorbable barbed sutures, STRATAFIX Spiral PDS Plus and STRATAFIX Spiral MONOCRYL Plus, compared with traditional sutures made of the same material in the suturing of thyroid surgery incision. - Source: PubMed
Publication date: 2026/09/02
Zou XiuheZhang TingZhao WenxinWu YijunWei WeiLu XiuboTeng ChangshengHuang TaoShen MeipingSchmitz Niels-DerrekIlie BogdanQu ShunZhang Hao - FADD (Fas-Associated Death Domain) protein in patients' serum and synovial fluid could be a biomarker of inflammation in rheumatic diseases. We tested whether the baseline serum FADD level would be a predictive factor for meeting the American College of Rheumatology (ACR)/EULAR 2010 criteria for rheumatoid arthritis (RA) in order to facilitate the early diagnosis of RA. - Source: PubMed
Falgarone GéraldineMouasni SaraMistou SylvieDevauchelle-Pensec ValérieGottenberg Jacques-EricChiocchia GillesTourneur Léa - Genomic imprinting results in parent-of-origin-dependent gene expression, but how three-dimensional genome organization contributes to imprinted gene regulation remains unclear. Using Capture Hi-C in mouse cortex and primary cortical neurons, we identified parental allele-specific chromatin architectures across multiple imprinted domains. These architectures largely originate from imprinting control regions and correlate with DNA methylation-sensitive CTCF binding. Active and inactive alleles of imprinted genes show distinct promoter interaction profiles and differential engagement with distal regulatory elements in both contact frequency and the epigenetic state of distal regions. A CRISPR interference screen identified a distal enhancer that regulates Mest-Copg2 imprinted expression through allele-specific chromatin interactions. In neurons, this enhancer activates Copg2 on the maternal allele, whereas on the paternal allele it drives Mest isoforms transcribed antisense to Copg2 and contributes to Copg2 repression. In summary, we show that allele-specific chromatin architecture coordinates maternal enhancer activity and paternal antisense transcription to control imprinted expression in neurons. - Source: PubMed
Publication date: 2026/08/08
Bae BongminGu KatherineLoftus DanielWhipple Amanda J - Physical inactivity and reduced quality of life are common in patients undergoing maintenance hemodialysis. Although intradialytic exercise has been extensively investigated, the effects of structured pre-dialysis exercise combined with breathing techniques on mental well-being, hemodynamic parameters, and dialysis adequacy remain unclear. This study aimed to evaluate the impact of a pre-dialysis structured exercise program on quality of life, hemodynamic status, and dialysis adequacy in maintenance hemodialysis patients. - Source: PubMed
Publication date: 2026/09/01
Zorlu Görgülügil GizemÜnal AysunNazik GamzeKocabıyık EsraKocabıyık Alperen BurakKöker GökhanYılmaz Üstün - remains a serious global health threat due to rapid progression, high mortality and rising antibiotic resistance. FabF, a key enzyme in the bacterial fatty acid synthesis (FAS II) pathway, is a promising target for new antimicrobials. A 3D model of FabF was constructed and validated and 2,583 marine natural compounds were screened for drug-likeness and ADMET properties. Molecular docking of 241 selected compounds identified three candidates with stronger binding affinity than minocycline. Compounds CMNPD5392, CMNPD14910 and CMNPD14926 showed promising interactions, indicating potential as FabF-targeted therapeutics. - Source: PubMed
Publication date: 2026/06/30
Kumari PriyankaRanga DikshaYadav PoojaSaini VandanaKumar Ajit