S100B, human, recombinant, full length
- Known as:
- S100B, H. sapiens, Rec., length
- Catalog number:
- 201SB01
- Product Quantity:
- 100ug
- Category:
- -
- Supplier:
- ProtEra
- Gene target:
- S100B human recombinant full length
Related genes to: S100B, human, recombinant, full length
- Gene:
- S100B NIH gene
- Name:
- S100 calcium binding protein B
- Previous symbol:
- -
- Synonyms:
- S100beta
- Chromosome:
- 21q22.3
- Locus Type:
- gene with protein product
- Date approved:
- 1988-06-27
- Date modifiied:
- 2014-11-18
Related products to: S100B, human, recombinant, full length
Related articles to: S100B, human, recombinant, full length
- As a blood biomarker associated with cerebral infarction (CI), the ultrasensitive detection of S100 calcium-binding protein B (S100B) is of great significance for the early warning of CI. Electrochemiluminescence (ECL) technology holds tremendous application potential due to its high sensitivity and low background noise. However, the further expansion of ECL applications is often limited by low efficiency. In particular, gold nanoclusters (NCs) typically undergo significant nonradiative decay due to the vibrational and rotational motion of their ligands. Regulating the metal-organic frameworks structure and synergistically enhancing it with coreactant accelerators is an effective strategy to overcome this performance bottleneck. In this study, we constructed an ECL system with dual enhancement effects of emitter and coreactant sides. At the emitter side, bovine serum albumin (BSA)-stabilized AuNCs (BSA-AuNCs) were loaded onto pleated Ce-MOF (B-AuNCs/Ce-MOF), and nonradiative decay was suppressed through the rigidification effect, resulting in 1.73 times the ECL efficiency of BSA-AuNCs. At the coreactant side, NiFe-PBA nanomaterials (Ni/Fe precursor molar ratio of 3:2) were engineered to serve as coreactant accelerators. Density functional theory (DFT) calculations indicated that the model constructed with a Ni/Fe precursor ratio of 3:2 exhibited the most favorable adsorption energy of TEA, with an adsorption energy of -0.432 eV. Consequently, the B-AuNCs/Ce-MOF+NiFe-PBA system exhibited 2.12 times the ECL efficiency of BSA-AuNCs. Based on this synergistically enhanced system, ultrasensitive detection of the CI biomarker S100B was achieved, with a linear range of 0.1 pg/mL-100 ng/mL and a detection limit of 0.03 pg/mL (S/N = 3). The method also demonstrated excellent stability, reproducibility and selectivity. This strategy provides a new approach for the early diagnosis and precise detection of acute CI. - Source: PubMed
Li NaChen JinguiJia DehaoDu YuRen XiangLi YueyunLee Jin YongWei Qin - Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by persistent deficits in social communication and the presence of restrictive, repetitive patterns of behaviour. Although its exact aetiology remains multifaceted and partially understood, recent clinical interest has shifted towards neurobiological substrates, specifically neuroaxonal and astroglial integrity. This study aims to compare serum levels of Neurofilament Light Chain (NfL), Glial Fibrillary Acidic Protein (GFAP), Tau and S100B between children with ASD and healthy controls, while investigating the influence of these biochemical variables on autism severity and behavioural manifestations. - Source: PubMed
Dedeoğlu Zeynep NurUzun NecatiKılınç İbrahimKılıç Ahmet Osman - The incidence of sports-related concussion (SRC) in rugby has been rising in recent years. The Head Injury Assessment (HIA) protocol, used to manage SRC, is limited by its reliance on subjective symptom reporting. Blood biomarkers such as glial fibrillary acidic protein (GFAP), ubiquitin C-terminal hydrolase L1 (UCH-L1) and S100B could serve as complementary objective tools for SRC management. - Source: PubMed
Publication date: 2026/08/14
Oris CharlotteGaulmin RémiDurif JulieGoddelière VincentPereira BrunoBouvier DamienSapin Vincent - In Hirschsprung disease (HD), intraoperative identification of ganglionated bowel remains central to surgical planning, particularly in extensive or near-total intestinal aganglionosis (nTIA), where bowel preservation is critical. Frozen-section histopathology remains the intraoperative standard. Ex-vivo fluorescence confocal microscopy (FCM) provides microscopic assessment of fresh tissue, while rapid immunofluorescence (rIF) has the potential to add targeted visualization of enteric neural structures. We describe a single pediatric proof-of-concept case in which FCM combined with selected rIF was integrated into intraoperative intestinal mapping. - Source: PubMed
Publication date: 2026/07/29
Di Fabrizio DonatellaLa Contana AlessandraBindi EdoardoCruccetti AlbaGoteri GaiaCobellis Giovanni - Neurological injury remains an important concern in paediatric patients after congenital heart disease (CHD) surgery with cardiopulmonary bypass (CPB). Regional cerebral oxygen saturation (rScO) can be used to identify unstable intraoperative cerebral oxygenation, but its association with the postoperative responses of brain injury biomarkers remains unclear. - Source: PubMed
Publication date: 2026/07/29
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