Apo CIII Antibody, pAb, Goat
- Known as:
- Apo CIII Antibody, pAb, Goat
- Catalog number:
- A00124
- Product Quantity:
- 100ug
- Category:
- -
- Supplier:
- Genscript
- Gene target:
- Apo CIII Antibody pAb Goat
Related genes to: Apo CIII Antibody, pAb, Goat
- Gene:
- ADAM18 NIH gene
- Name:
- ADAM metallopeptidase domain 18
- Previous symbol:
- -
- Synonyms:
- tMDCIII, ADAM27
- Chromosome:
- 8p11.22
- Locus Type:
- gene with protein product
- Date approved:
- 1998-12-01
- Date modifiied:
- 2018-05-03
Related products to: Apo CIII Antibody, pAb, Goat
Related articles to: Apo CIII Antibody, pAb, Goat
- The success of spermatogenesis depends on the interplay of various biomolecules that ultimately determine sperm quality. In this study, RNA-seq analysis of frozen-thawed buffalo sperm (n = 8) revealed the presence of 263 mineral-associated genes (>1 FPKM) in high (n = 4) and 181 in low motile (n = 4) sperm groups. Among these, 177 mineral-associated genes were commonly expressed between them, and the majority were upregulated (>1 fold), LOC102391588 (ncRNA; 37-fold), ZNF699 (26.5-fold), MYZAP (13-fold), etc., in the high motile group. The expression of selected mineral-associated genes was validated. The top enriched functions in commonly expressed genes were regulation of transcription by RNA polymerase II (FDR: 4.7 × 10⁻; ZNF331, ZNF692, ZNF180, etc.), followed by spermatogenesis (FDR: 2.9 × 10⁻; CALR3, ADAM18, ADAM9, etc.), proton transmembrane transport (FDR: 4.0 × 10⁻; ATP6V0E1, ATP1A4, ATP6V1B2, etc.) and flagellated sperm motility (FDR: 2.3 × 10⁻; CATSPERD, EFCAB6, CABS1, etc.). Additionally, the chromatin remodeling pathway (FDR: 3 × 10⁻; PTP4A1, PPM1A, DUSP1, etc.) emerged as the most significant and may suggest that these minerals influence genome packaging and sperm functionality. Mineral-associated genes were predominantly associated with zinc (49%), followed by calcium (20%), phosphorus (10%), iron (5%), sodium (2%), potassium (2%), copper (1%) and other trace elements (11%). Although the current study uses frozen-thawed sperm, the findings indicate that mineral-associated genes are crucial for promoting membrane stability, energy production, motility and chromatin integrity, which may contribute to the superior fertilizing ability of sperm. - Source: PubMed
Publication date: 2026/08/14
Manjunatha A TShalini RBinsila B KKrishnappa BRajendran DAthira TParvathi KSahoo ASelvaraju S - Hexi cattle are a local cattle population endemic to the Hexi Corridor in Gansu Province, China, and exhibit strong adaptability to the region's arid continental environment. However, comprehensive genomic investigations of this population are still lacking. In the present study, we integrated population genomic analyses with a genome-wide association study (GWAS) to dissect the genetic architecture of Hexi cattle. Whole-genome resequencing data were generated for 264 Hexi cattle, and public genomic datasets from six representative cattle breeds were obtained from the NCBI database for comparative analysis. Multiple analytical approaches-including principal component analysis (PCA), linkage disequilibrium (LD) decay analysis, neighbor-joining (NJ) phylogenetic tree construction, and ADMIXTURE analysis-were adopted to evaluate population structure and evolutionary relationships. A mixed linear model was then used to identify significant SNPs associated with five major body conformation traits in six-month-old cattle: body weight (BW), withers height (WH), hip height (HH), heart girth (HG), and abdominal girth (AG). Our results confirm the admixed nature of Hexi cattle, whose genome is derived primarily from Simmental cattle and secondarily from Mongolian cattle. A total of 69 trait-associated significant SNPs were identified and functionally annotated. Specifically, , and were linked to BW; and to WH; to HH; , , and to HG; and , , , , , , and M18 to AG. This study deepens our understanding of the genetic basis of growth traits in Hexi cattle and offers valuable molecular resources for future selective breeding, genetic improvement, and long-term conservation of this indigenous cattle population. - Source: PubMed
Publication date: 2026/07/16
Wang XinluMa BinWang ZhichengLiu YichengMa XiaomingChu MinLa YongfuGuo XianYan PingWang LeiLiang Chunnian - Hepatocellular carcinoma (HCC) is the most common primary liver cancer worldwide. Cancer cells' local infiltration, proliferation, and spread are mainly influenced by the protein hydrolyzing function of different matrix metalloproteinases (MMPs). However, no study has determined the relationship between MMPs and prognostic prediction in HCC. - Source: PubMed
Publication date: 2024/05/16
Yuan XingxingYang LiuxinGao JiaweiMao XuZhang YaliYuan Wei - The current study aims to determine the molecular mechanisms of diabetic retinopathy (DR) using the protein-protein interactome and metabolome map. We examined the protein network of novel biomarkers of DR for direct (physical) and indirect (functional) interactions using clinical target proteins in different models. - Source: PubMed
Publication date: 2020/06/18
Patrick Ambrose TeruHe WeilueMadu JoshuaSripathi Srinivas RChoi SeulggieLee KookSamson Faith PwaniyiboPowell Folami LBartoli ManuelaJee DonghyunGutsaeva Diana RJahng Wan Jin - Cancer-associated fibroblasts (CAFs) are important factors in the progression of hepatocellular carcinoma (HCC). But the characterization of these cells remains incomplete. This study aims to identify a panel of markers for CAFs that are associated with HCC progression. - Source: PubMed
Publication date: 2018/11/05
Zou BaojiaLiu XialeiGong YihangCai ChaonongLi PeipingXing ShanPokhrel BibeshZhang BaimengLi Jian