c_Jun Antibody (Ab_63), pAb, Rabbit
- Known as:
- c_Jun Antibody (Ab_63), pAb, Rabbit
- Catalog number:
- A00580
- Product Quantity:
- 200ug
- Category:
- -
- Supplier:
- Genscript
- Gene target:
- c_Jun Antibody (Ab_63) pAb Rabbit
Related products to: c_Jun Antibody (Ab_63), pAb, Rabbit
Related articles to: c_Jun Antibody (Ab_63), pAb, Rabbit
- Aqueous zinc-ion batteries (ZIBs) represent a transformative energy storage technology for next-generation flexible electronics, yet their practical implementation has been constrained by persistent challenges including uncontrolled zinc dendrite growth and the inherent trade-off between ionic conductivity (IC) and mechanical strength of hydrogel electrolytes. In this study, a hydrogel electrolyte (SBD) was fabricated by combining sodium alginate (SA) with diethylenetriaminepentaacetic acid (DTPA)-functionalized bacterial cellulose (BC). Its hierarchically porous 3D network and abundant carboxylate groups (-COO) simultaneously homogenized Zn flux, constructed favorable spatial coordination sites for Zn, and strengthened mechanical integrity. The electrolyte exhibited an IC of 45.5 mS cm, a tensile strength of 435 kPa, and a Zn transference number (tZn) of 0.71. The as-assembled Zn/SBD/Zn symmetric cell delivered stable cycling over 3500 h at 1 mA cm, while the Zn/SBD/MnO full cell maintained 76.9% capacity retention after 500 cycles. Flexible Zn/SBD/MnO batteries retained stable electrochemical performance under bending deformation, indicating their potential for durable wearable energy storage applications. - Source: PubMed
Publication date: 2026/09/23
Li FaguoYu XinranDing YangyangTian ZhongdongZhao NanaShi FengweiMei Jun - Acute appendicitis is the most common surgical emergency worldwide. Concern that delayed treatment might increase perforation can lead to unnecessary surgery and high rates of negative appendicectomy, where a normal, non-inflamed appendix is removed. However, whether perforation is related to pre-hospital time (symptom onset to first surgical assessment) has not been explored in contemporary global data. - Source: PubMed
Publication date: 2027/06/02
Anyomih Theophilus T KAregawi Alazar BCalvache Jose ADawson AmandaIsik ArdaLapitan Marie CPata FrancescoQureshi Ahmad UZarour Ahmad M ABhangu AneelNepogodiev Dmitri - - Source: PubMed
Publication date: 2027/06/02
Molla Yohannis Derbew - Compromised bone quality predisposes domesticated birds to fractures in meat ducks, leading to pain and bad welfare. As a fermentable type II resistant starch, raw potato starch (RPS) probably supports gut health and potentially mitigate this inflammatory bone loss. Accordingly, the physicochemical properties of RPS were characterized, and its protective effect on bone quality in meat ducks were evaluated in the present study. The outcomes from electron microscope and X-ray diffraction showed that RPS possessed a round or oval granules with a smooth surface and a B-type crystalline structure. Subsequently, a total of 60 1-day-old meat ducks were randomly assigned to two treatment groups and fed either a basal diet or a diet containing 12% RPS until 21 d (Animal trial 1). The results revealed that dietary supplementation of RPS increased (P < 0.05) tibial ash content of meat ducks, which negatively correlated gut leak and serum inflammatory status. To confirm the protective role of RPS in enteritis-induced bone loss in meat ducks. Ducklings were allocated to a phosphate-buffered saline control group, dextran sodium sulphate (DSS) oral administration group, and DSS treatment and fed a 12% RPS diet group with 8 repetitions of 10 birds each to 21 d (Animal trial 2). Duck challenged DSS exhibited increased bone resorption and compromised tibia density and mechanical properties (P < 0.05). DSS treatment downregulated the expressions of tight junction proteins and triggered intestinal inflammation in ileum, whereas failed to change the composition of caecal microbiota. In meat ducks with DSS-induced enteritis, feeding a diet of RPS reversed inflammation-induced bone loss. This effect was accompanied by increased serum phosphorus levels (P < 0.05) and reduced pro-inflammatory cytokines in the bone marrow microenvironment, leading to decreased osteoclastic bone resorption. These findings support that a diet with 12% RPS might be one of promising holistic approaches for mitigating systemic inflammation and consequent bone loss in meat ducks. - Source: PubMed
Publication date: 2026/06/22
Yue XinYu JingyiHou YuhuangNguyen Minh TuSi XuemengZheng RuiChen WenHuang YanqunZhang Huaiyong - Super-enhancers are clusters of cis-regulatory elements that sustain the expression of cell-identity genes. Their aberrant activation or dysfunction constitutes a hallmark of malignant cellular transformation, which frequently rewires oncogenic transcriptional programs to support uncontrolled cell proliferation and metastatic potential. However, the functions and epigenetic regulation mechanisms of colorectal cancer specific super-enhancers remain poorly understood, and few studies have focused on dissecting how tumor enriched super-enhancers mediate downstream oncogenic signaling in CRC. By integrating multi-omics sequencing data, we identified a highly active super-enhancer in colorectal cancer, termed DCBLD2-SE. Through luciferase reporter assays, the SE3-2 subregion was identified as the minimal functional core of this super-enhancer. Mechanistic studies confirmed that transcription factors of the activator protein-1 family (FOSL2 and JUND) can bind directly to the SE3-2 cis-regulatory element, synergistically regulating local chromatin remodeling and strongly driving the upregulation of the target gene DCBLD2. Following knockout of the DCBLD2-SE core region, the malignant proliferative capacity of colorectal cancer cells decreased significantly, and the growth of xenograft tumors in vivo was markedly inhibited. Functionally, DCBLD2-SE facilitates tumor progression through a DCBLD2-dependent CD146/AKT/TNFRSF6B signaling axis. Clinically, high expression of DCBLD2 correlates with malignant metastasis and poor overall survival in patients with colorectal cancer. In summary, this study uncovers a previously undescribed DCBLD2-centered regulatory cascade that promotes colorectal cancer initiation and progression. DCBLD2-SE and its binding transcription factor activator protein-1 represent promising prognostic biomarkers and actionable therapeutic targets for colorectal cancer. - Source: PubMed
Publication date: 2026/09/23
Wu TongShao LanHu XinHe HongjuanChen LuFeng MeiqiQi ChengjinWang ZiwenYu HaoranJi BoshuCao YijiaZhang YanWu Qiong