Human VDBP ELISA kit (10X96T)
- Known as:
- Human VDBP Enzyme-linked immunosorbent assay test reagent (10X96T)
- Catalog number:
- LF-EK0143
- Product Quantity:
- 10×96T
- Category:
- Peptides
- Supplier:
- Abfron
- Gene target:
- Human VDBP ELISA kit (10X96T)
Related genes to: Human VDBP ELISA kit (10X96T)
- Gene:
- GC NIH gene
- Name:
- GC vitamin D binding protein
- Previous symbol:
- -
- Synonyms:
- DBP, VDBP, hDBP
- Chromosome:
- 4q13.3
- Locus Type:
- gene with protein product
- Date approved:
- 1986-01-01
- Date modifiied:
- 2019-01-25
Related products to: Human VDBP ELISA kit (10X96T)
Related articles to: Human VDBP ELISA kit (10X96T)
- The attitude towards using glucocorticosteroids (GCs) for the management of patients with systemic lupus erythematosus (SLE) has undergone drastic changes over the last decades. While the role of GCs for the rapid control of inflammation is uncontested, the former 'dogma' that GCs must never be withdrawn due to fear of severe flares was proven wrong and replaced by a strategy that invites both tapering GCs to 0 and questioning whether they even need to be initiated at all in individual patients. Moreover, the daily prednisone equivalent dose acceptable for long-term use is limited to ≤ 5 mg in current recommendations. These changes are a consequence of a substantial body of evidence that links higher GC doses to infections, cardiovascular events and other damage, and an increasing number of studies showing that GC withdrawal is feasible in many SLE patients who are in remission. Despite methodological concerns, with observational data inherently prone to confounding by indication, the worldwide experience of the last decades suggests that the limit of 5 mg daily is justified. Moreover, current strategies and novel medications have made it a reality for many SLE patients, to actually maintain the goal of remission or low disease activity on not >5 mg of prednisone per day. - Source: PubMed
Publication date: 2026/06/30
Fanouriakis AntonisAringer Martin - Norovirus is a leading cause of acute gastrointestinal illness (AGI). Norovirus is not notifiable in the United States; therefore, health departments typically only receive reports of norovirus outbreaks. While wastewater surveillance has been demonstrated to be useful for tracking community norovirus case reports, its value during outbreak investigations is less understood. This study evaluates the impact of a single norovirus outbreak on wastewater measurements in a community. Norovirus genogroup 2 (GII) concentrations were measured at two wastewater treatment facilities (WWTFs) near a restaurant experiencing a norovirus GII outbreak (Restaurant A). The largest increase in norovirus GII RNA concentrations (increase of 13,111.8 gc/mL) at the WWTF serving Restaurant A (WWTF A) occurred on the same day most (44%) outbreak case patients reported symptom onset. This increase occurred 1 day before the outbreak was reported to public health, 2 days before norovirus was identified in clinical specimens, and 3 days before clinical specimens were genotyped at the public health laboratory. At a second local WWTF, WWTF B, norovirus GII RNA concentrations also increased at the same time but peaked 2 days after WWTF A. These findings suggest wastewater measurements can serve as a leading indicator of norovirus outbreaks and inform outbreak response efforts. - Source: PubMed
Publication date: 2026/05/20
McGinnis ShannonNegrón Elizabeth ACesari NickBrooks Yolanda MJones Matthew JMcGraw Elizabeth AFidler Bevin DurantZwolenik KristinaLund Hannah - Here, we report the complete genome sequence of sp. 20-5, a potent biocontrol bacterium isolated from a soil sample of Chongqing, China. The genome consists of 6,335,883 bp with a GC content of 66.51%, in which 5,729 protein-coding genes, 12 rRNA, and 65 tRNA genes were identified. - Source: PubMed
Publication date: 2026/06/29
Li XinyueLi XiaoqingLan XiqianHu JunhuaXie JieZhou ZeyangWei Junhong - Chemotactic receptors involved in generation of ectopic pulmonary germinal centers (GCs) within inducible bronchus-associated lymphoid tissue (iBALT) are poorly defined. Here, using CIBER -reporter mice, we demonstrate that the prototypical type 1 inflammatory chemokine receptor CXCR3 is highly induced in influenza A virus (IAV)-reactive B cells in the mediastinal lymph node, spleen, lung, peripheral blood, and airways following intranasal infection. Notably, elevated was observed in ectopic pulmonary germinal center B (GCB) cells in iBALT relative to their contemporaneous counterparts in secondary lymphoid organs across the timecourse of the response to IAV infection. Mice with a B cell-specific deletion of displayed a 50 to 60% reduction in the frequency and number of ectopic GCB cells in the lungs at the peak of the response following IAV infection, relative to controls. Furthermore, in cotransfers, -deficient B cells were substantially outcompeted by their -sufficient counterparts for ectopic pulmonary GC participation, but were not impacted with respect to GCB cell frequencies in other compartments. Thus, the data elucidate the requirement of B cell-intrinsic CXCR3 expression for efficient generation of ectopic pulmonary GCB cell responses in iBALT following respiratory viral infection with IAV, a finding that broadens understanding of the molecular cues underpinning this key component of local protective humoral immunity to IAV. - Source: PubMed
Publication date: 2026/06/30
Tyllis Timona SNorton Todd SAbbott CaitlinMcPeake Dylan JFenix Kevin AWilson Jasmine JKara Ervin EGood-Jacobson Kim LAlsharifi MohammedMcColl Shaun RComerford Iain - - Source: PubMed