0.75 mm Compact Multi Gel Cast
- Known as:
- 0.75 millimeter Compact Multi Gel Cast
- Catalog number:
- 2322602
- Category:
- -
- Supplier:
- Ato
- Gene target:
- 0.75 Compact Multi Gel Cast
Related genes to: 0.75 mm Compact Multi Gel Cast
- Gene:
- ABCC3 NIH gene
- Name:
- ATP binding cassette subfamily C member 3
- Previous symbol:
- -
- Synonyms:
- MRP3, cMOAT2, EST90757, MLP2, MOAT-D
- Chromosome:
- 17q21.33
- Locus Type:
- gene with protein product
- Date approved:
- 1999-10-26
- Date modifiied:
- 2018-05-03
- Gene:
- ADGRF5 NIH gene
- Name:
- adhesion G protein-coupled receptor F5
- Previous symbol:
- GPR116
- Synonyms:
- DKFZp564O1923, KIAA0758
- Chromosome:
- 6p12.3
- Locus Type:
- gene with protein product
- Date approved:
- 2002-11-26
- Date modifiied:
- 2015-03-03
- Gene:
- ANGEL1 NIH gene
- Name:
- angel homolog 1
- Previous symbol:
- KIAA0759
- Synonyms:
- Ccr4e
- Chromosome:
- 14q24.3
- Locus Type:
- gene with protein product
- Date approved:
- 2003-11-21
- Date modifiied:
- 2016-06-29
- Gene:
- ANGEL2 NIH gene
- Name:
- angel homolog 2
- Previous symbol:
- -
- Synonyms:
- KIAA0759L, FLJ12793, Ccr4d
- Chromosome:
- 1q32.3
- Locus Type:
- gene with protein product
- Date approved:
- 2005-08-04
- Date modifiied:
- 2016-06-29
- Gene:
- ASNSD1 NIH gene
- Name:
- asparagine synthetase domain containing 1
- Previous symbol:
- -
- Synonyms:
- NS3TP1, FLJ20752, NBLA00058
- Chromosome:
- 2q32.2
- Locus Type:
- gene with protein product
- Date approved:
- 2006-02-13
- Date modifiied:
- 2015-08-28
Related products to: 0.75 mm Compact Multi Gel Cast
Related articles to: 0.75 mm Compact Multi Gel Cast
- Computational phenomenology has been recently presented as a novel and promising approach to modelling human experience with the use of computational techniques. More specifically, as it has been discussed in recent work, it links phenomenological descriptions and analyses of lived experience and generative modelling techniques, most prominently, through Active Inference. It is argued that the experiential disclosure of the world and time-consciousness can be cast in terms of free energy minimization and inferential dynamics. It has not been addressed yet, however, whether and to what extent Active Inference may be able to model fundamental structures that constitute what phenomenologists call 'motor intentionality', i.e. our general embodied and practical openness to our experiential world. This openness is taken to underlie all experience. To address this gap in the literature, we propose to distinguish two different kinds of practical aspects within Active Inference. First, we discuss the approximation to a true posterior as a form of active process that can be linked with some of the core characteristics of what phenomenologists call 'passive syntheses'. Secondly, we discuss the process of action selection under likelihood mappings and preferences and link it with the constitution of a field of affordances of an embodied subject, as well as with the idea that the body is 'the first prior' within an Active Inference model. This embodied constitution is the core of what phenomenologists call 'motor intentionality'. Insofar as these two practical aspects of Active Inference are processes undertaken within the model, we emphasize the temporality that underlies them in terms of subjective temporality and objective time. - Source: PubMed
Publication date: 2026/09/21
Djebbara ZakariaBogotá Juan Diego - Real-world long-term data on oral semaglutide are limited. We evaluated its 24-month effectiveness, persistence, and safety in adults with type 2 diabetes (T2D). - Source: PubMed
Publication date: 2026/09/21
Baldassarre Maria Pompea AntoniaDi Dalmazi GiuliaCarrieri FedericaCentorame GiorgiaPiacentino LuigiColuzzi SaraFormoso Gloria - Ex vivo genome editing of hematopoietic stem and progenitor cells (HSPCs) holds significant therapeutic potential but remains constrained by genotoxic risks associated with nuclease-induced DNA double-strand breaks, DNA donor template delivery and sensing, and proliferation-induced stress during ex vivo manipulation. These processes can lead to chromosomal instability, large on-target deletions, donor mis-integration, off-target events, and impaired long-term stem cell function, raising safety concerns for clinical translation. Here, we evaluate the impact of transient p38 MAPK inhibition on genomic integrity during clinically relevant CRISPR-Cas9 editing and show that this intervention attenuates ex vivo culture-associated stress without increasing detectable genotoxic outcomes. Comprehensive genotoxicity analyses, including quantification of large on-target deletions, adeno-associated viral vector mis-integration, and CAST-seq mapping of translocations, reveal no measurable differences in gene editing-associated structural alterations upon p38 MAPK inhibition, while micronuclei were significantly reduced. Importantly, long-term xenotransplantation followed by whole-exome sequencing shows that p38i-treated HSPCs display a reduced mutational burden without evidence of increased genomic alterations. Collectively, these findings identify transient p38 MAPK inhibition as a strategy to improve the quality and long-term fitness of gene-edited HSPCs without detectable adverse effects on the genome editing outcomes, supporting its further evaluation as a refinement to clinically relevant CRISPR-Cas9 editing workflows. - Source: PubMed
Publication date: 2026/09/22
Vacca RobertaDella Volpe LucreziaGualandi NicolòShiroshita KoheiCarsana EdoardoGiannetti KetyGaddoni ChiaraBenedicenti FabrizioGega BarbaraArévalo SergioZarghamian ParinazBeretta StefanoCastiello Maria CarminaBrombin ChiaraCanarutto DanieleMerelli IvanCathomen ToniMontini EugenioVilla AnnaNaldini LuigiDi Micco Raffaella - Near-term quantum algorithms are a promising route to solving partial differential equations, but gauging their true potential requires separating algorithmic performance from sampling and hardware noise. We benchmark a ground-state variational quantum eigensolver (VQE), cast as a variational quantum linear solver, against the Trotterization, variational quantum imaginary time evolution, and adaptive variational quantum dynamics simulation methods applied to the one-dimensional advection-diffusion equation in the recent quantum-dynamics study by Alipanah et al. [Phys. Rev. Res. 7, 043318 (2025)2643-156410.1103/ndc3-bdwt] at matched grid and problem size. On a noiseless state-vector simulator the N=4 VQE drives the final-time infidelity to a numerical floor (∼10^{-14}) once the depth reaches L≈5, an algorithmic ceiling set by exact expectation values. Evaluating the same solver with a finite number S of measurement shots, still without hardware noise, makes the infidelity sampling limited, following 1-f≈c/S (a best-case readout-sampling estimate, with the solution's signs assumed known), providing a regime-matched comparison with the shot-based emulator of Alipanah et al. and explaining the gap to their noisy hardware runs (>10^{-1}). The benchmark thus decomposes the near-term error budget into algorithmic, sampling, and hardware contributions, with a matched-depth resource comparison. The formulation applies without modification across N=4,5,6 qubits and to a two-dimensional (eight-qubit, 16×16) problem evolved to t=1, where the state-vector VQE holds a ∼10^{-7} algorithmic-ceiling infidelity against the sampling-limited ∼10^{-5} of the corresponding shot-based simulation, a difference of measurement regime rather than algorithmic superiority. - Source: PubMed
Özgüler A Barış - Two-dimensional van der Waals semiconductors promise low-power chemical perception at room temperature, yet contact-limited on-currents and slow recovery impede closed-loop decision making in hazardous environments. Here we propose antimony (Sb)-contact two-dimensional (2D) monolayer MoS field-effect transistors (FETs) that leverage contact engineering to boost on-current and charge-transfer gas response for room temperature detection and enable electrically programmable recovery via pre-bias pulses that actively accelerate desorption and baseline restoration. The Sb-contact MoS FETs show unprecedented ppb gas response (363,600% at 500 ppb NO) and rapid, repeatable room temperature recovery with ultra-low energy consumption (42 pJ, representing the intrinsic energy efficiency of the sensing front-end), serving as a proof-of-concept for the front-end of a safety-constrained reinforcement-learning (RL) stack that detects leak sources and plans low-risk escape path in turbulent interiors. We cast joint seek-and-escape as a single constrained Markov decision process informed by real-time transduction features fused with thermal-flow cues; the learned policy achieves earlier detection, lower cumulative exposure, and shorter safe-egress paths than heuristic baselines in computational fluid dynamics (CFD)-validated simulations and chamber trials. By uniting contact-engineered 2D transducers with risk-aware RL, this work advances room temperature chemical sensing from passive monitoring to closed-loop action. - Source: PubMed
Publication date: 2026/09/22
Cho YoungchanPyo JinhyeokShin YeonseopKang Min WookOh YebinHwang Se-HyunPark SohyeonRadermacher DavidOh SaeroonterKwon DaewoongLee Sung-TaeChoi JunhoKim JangsaengShin WonjunPak Sangyeon