GATA3 Monoclonal Antibody [1C1] 100 µg
- Known as:
- GATA3 Monoclonal Antibody [1C1] 100 µg
- Catalog number:
- ABB-2238-100
- Product Quantity:
- 100 µg
- Category:
- -
- Supplier:
- EpigenTek
- Gene target:
- GATA3 Monoclonal Antibody [1C1] 100 µ
Related genes to: GATA3 Monoclonal Antibody [1C1] 100 µg
- Gene:
- C1orf174 NIH gene
- Name:
- chromosome 1 open reading frame 174
- Previous symbol:
- -
- Synonyms:
- RP13-531C17.2
- Chromosome:
- 1p36.32
- Locus Type:
- gene with protein product
- Date approved:
- 2005-07-21
- Date modifiied:
- 2017-07-11
- Gene:
- CBR1 NIH gene
- Name:
- carbonyl reductase 1
- Previous symbol:
- CBR
- Synonyms:
- SDR21C1
- Chromosome:
- 21q22.12
- Locus Type:
- gene with protein product
- Date approved:
- 1991-02-20
- Date modifiied:
- 2016-10-05
- Gene:
- DLG1 NIH gene
- Name:
- discs large MAGUK scaffold protein 1
- Previous symbol:
- -
- Synonyms:
- SAP97, SAP-97, hdlg, DLGH1, dJ1061C18.1.1
- Chromosome:
- 3q29
- Locus Type:
- gene with protein product
- Date approved:
- 1995-05-04
- Date modifiied:
- 2016-05-24
- Gene:
- DNAAF4 NIH gene
- Name:
- dynein axonemal assembly factor 4
- Previous symbol:
- DYX1C1
- Synonyms:
- EKN1, FLJ37882, CILD25
- Chromosome:
- 15q21.3
- Locus Type:
- gene with protein product
- Date approved:
- 2003-10-10
- Date modifiied:
- 2017-03-20
- Gene:
- DNAAF4-CCPG1 NIH gene
- Name:
- DNAAF4-CCPG1 readthrough (NMD candidate)
- Previous symbol:
- DYX1C1-CCPG1
- Synonyms:
- -
- Chromosome:
- 15q21.3
- Locus Type:
- readthrough
- Date approved:
- 2011-09-23
- Date modifiied:
- 2017-03-23
Related products to: GATA3 Monoclonal Antibody [1C1] 100 µg
Related articles to: GATA3 Monoclonal Antibody [1C1] 100 µg
- ALK-negative anaplastic large cell lymphoma (ALK-negative ALCL) frequently expresses cytotoxic molecules, which may complicate its distinction from peripheral T-cell lymphoma NOS (PTCL-NOS), particularly in cytotoxic molecule-positive cases. Among these, nodal EBV-negative cytotoxic T-cell lymphoma (CTL) represents an important diagnostic consideration. We evaluated the clinicopathological features of ALK-negative ALCL in comparison with nodal EBV-negative CTL and ALK-positive ALCL, with a focus on the immunohistochemical expression of master transcription factors (RORγt, T-bet, and GATA3). RORγt expression was significantly more frequent in ALK-negative ALCL than in nodal EBV-negative CTL (11/21 [52%] vs. 2/25 [8%]; P=0.001), and was uniformly present in ALK-positive ALCL (10/10 [100%]; P=0.012 vs. ALK-negative ALCL). In contrast, T-bet expression was less frequent in ALK-negative ALCL (2/21 [10%]) than in nodal EBV-negative CTL (9/25 [36%]; P=0.045), and was absent in all ALK-positive ALCL cases. RORγt and T-bet expression were largely mutually exclusive across the cohort, with only one overlapping case. GATA3 expression was absent in all evaluable cases of nodal EBV-negative CTL and ALK-positive ALCL, and was detected in only 2 of 19 ALK-negative ALCL cases (11%). These findings suggest that ALK-negative ALCL shows a distinct transcription factor profile characterized by frequent RORγt expression and infrequent T-bet expression, in contrast to nodal EBV-negative CTL. Assessment of these markers may provide a useful adjunct in the differential diagnosis of cytotoxic T-cell lymphomas, particularly in diagnostically challenging cases. - Source: PubMed
Publication date: 2026/09/03
Muramatsu AyaYamashita DaisukeTsuyuki YutaSatou AkiraAsano NaokoHosoda WakiKarube KennosukeNakamura ShigeoKato Seiichi - The prevalence of food allergy has been rising over the past decade, but effective treatments remain limited. The purpose of this study was to investigate the effect of ginkgolide B (GB), a natural bioactive compound with well-documented anti-inflammatory and immunoregulatory properties, on a mouse model of food allergy and to elucidate the mechanism mediated by the mTOR signaling pathway. - Source: PubMed
Publication date: 2026/08/18
Zhou RongqinYang XiaotongTan PanpanWang HuanZeng DanMa Xiaojuan - Asthma is a chronic inflammatory airway disease characterized by Th2- dominant immune responses, airway hyperresponsiveness, and structural remodeling. Although inhaled corticosteroids and biologics are effective for many patients, a substantial proportion remains poorly controlled and experiences treatment-related adverse effects. Probiotics have emerged as immunomodulatory agents in asthma, but existing studies predominantly focus on oral administration and gut-lung axis regulation. Whether direct respiratory administration of probiotics can modulate the pulmonary immune microenvironment and alleviate asthma remains largely unexplored. - Source: PubMed
Publication date: 2026/09/01
Yang XinYu FanWu XiaochengLi ShuxianWang YingshuoHu ZhongXie YichengMa DaqingWu Lei - Loss of estrogen receptor (ER) and/or progesterone receptor (PR) might occur during the metastatic progression of ER positive and HER2 negative (ER+/HER2-) breast cancer (BC), but the underpinning molecular alterations remain elusive. We explored the genomic context of HER2- tumors with ER and/or PR loss to investigate potential drivers and actionable alterations that might help personalize treatment of ER+/HER2- BC. - Source: PubMed
Publication date: 2026/08/10
Migliaccio IleniaPaoli MartaBiagioni ChiaraGuarducci CristinaGalardi FrancescaAnichini GiuliaBiganzoli LauraBenelli MatteoMalorni Luca - Background, aim, and objectives: Accurate diagnosis of urothelial carcinoma (UC), particularly in high-grade and limited biopsy specimens, may be challenging on morphology alone. Immunohistochemistry (IHC) markers such as GATA3, uroplakin II (UPII), and p40 may improve diagnostic confidence. This study aimed to evaluate the diagnostic utility of GATA3, UPII, and p40, individually and as a combined panel, in urothelial carcinoma, and to correlate marker expression with tumor grade and invasion status. - Source: PubMed
Publication date: 2026/07/31
Manjari LavanyaM R AmruthaK R RameshP O VivekH Shruthi