Human Persephin (PSP) Source E. coli
- Known as:
- Human Persephin (PSP) Source E. coli
- Catalog number:
- 100-120
- Product Quantity:
- 20 µg
- Category:
- -
- Supplier:
- Reliatech
- Gene target:
- Human Persephin (PSP) Source . coli
Related genes to: Human Persephin (PSP) Source E. coli
- Gene:
- BPIFA2 NIH gene
- Name:
- BPI fold containing family A member 2
- Previous symbol:
- C20orf70
- Synonyms:
- bA49G10.1, SPLUNC2, PSP
- Chromosome:
- 20q11.21
- Locus Type:
- gene with protein product
- Date approved:
- 2001-07-17
- Date modifiied:
- 2015-12-07
- Gene:
- FCN2 NIH gene
- Name:
- ficolin 2
- Previous symbol:
- -
- Synonyms:
- P35, FCNL, EBP-37, ficolin-2
- Chromosome:
- 9q34.3
- Locus Type:
- gene with protein product
- Date approved:
- 1996-07-11
- Date modifiied:
- 2016-10-05
- Gene:
- FDPSP6 NIH gene
- Name:
- farnesyl diphosphate synthase pseudogene 6
- Previous symbol:
- FDPSP
- Synonyms:
- -
- Chromosome:
- 21q21.1
- Locus Type:
- pseudogene
- Date approved:
- 2000-05-23
- Date modifiied:
- 2014-11-19
- Gene:
- GPR45 NIH gene
- Name:
- G protein-coupled receptor 45
- Previous symbol:
- -
- Synonyms:
- PSP24, PSP24A
- Chromosome:
- 2q12.1
- Locus Type:
- gene with protein product
- Date approved:
- 1999-03-12
- Date modifiied:
- 2016-10-05
- Gene:
- GPR63 NIH gene
- Name:
- G protein-coupled receptor 63
- Previous symbol:
- -
- Synonyms:
- PSP24(beta), PSP24B
- Chromosome:
- 6q16.1
- Locus Type:
- gene with protein product
- Date approved:
- 2001-04-05
- Date modifiied:
- 2016-10-06
Related products to: Human Persephin (PSP) Source E. coli
Related articles to: Human Persephin (PSP) Source E. coli
- Down syndrome (DS), or trisomy 21 (T21), resulting from an extra copy of chromosome 21, occurs in 1 in 700-1,000 live births. Neuroinflammation is increasingly recognized as a critical contributor to DS neuropathology, although its underlying drivers remain unclear. - Source: PubMed
Publication date: 2025/12/05
Teles E Silva André LuízPrado de Oliveira Pedro HenriqueYokota-Moreno Bruno Yukioda Silva Fausto JéssicaAvila Jonatan PeñaNakaya Helder ISertié Andréa LauratoZampieri Bruna Lancia - Ficolins, encoded by FCN genes, are key pattern recognition molecules of the lectin complement pathway involved in immune complex clearance, a process often impaired in systemic lupus erythematosus (SLE). Genetic polymorphisms in FCN genes may influence disease susceptibility. However, their functional significance in SLE remains unclear. The present study aimed to investigate the association of selected FCN gene single-nucleotide polymorphisms (SNPs) with SLE, lupus nephritis (LN), and serum ficolin levels in a Western Indian cohort. Seven SNPs in FCN1 (rs2989727, rs1071583), FCN2 (rs7851696, rs17549193, rs7865453, rs17514136), and FCN3 (rs3813800) were genotyped in 200 SLE patients and 200 healthy controls using polymerase chain reaction (PCR) sequence-specific primer and PCR restriction fragment length polymorphism. Serum ficolin-1, -2, and -3 levels were measured using ELISA. Statistical analysis included χ2 test, Kruskal-Wallis test, and logistic regression to assess associations and calculate odds ratios with 95% confidence intervals. The analysis identified significant associations of FCN2 rs7851696, rs7865453, and rs17514136, as well as FCN3 rs3813800, with SLE susceptibility. Among LN patients, FCN1 rs2989727 and rs1071583, FCN2 rs17514136, and FCN3 rs3813800 showed significant associations. FCN3 rs3813800 was significantly associated with ficolin-3 levels, while FCN2 rs7865453 was associated with complement component 1q-circulation immune complex levels. These findings provide novel insight into associations of FCN gene polymorphisms with SLE and LN susceptibility, with genotype-phenotype correlations suggesting their biological relevance. Future longitudinal and mechanistic studies are warranted to validate these associations and explore their therapeutic potential. - Source: PubMed
Rai KirtiKhatri RidiJose AmruthaNadkar MilindRajadhyaksha AnjaliKonkar HarshadaSamant TrishaJaiswal PoojaDabholkar KunalPawaskar SwapnalMalik AmanParande AltafBitla GauthamiTapase PrashantPadwal VijayMadkaikar ManishaPradhan Vandana D - Multianalyte plasma proteomic panels that can accurately detect initial AD pathology in preclinical populations and simultaneously measure related biological processes relevant for disease risk are critical for advancing early detection and prognosis. - Source: PubMed
Publication date: 2025/10/24
Trelle Alexandra NCody Karly ANguyen Tran TWiner Joseph RWeiss SkylarSai IshaChannappa DivyaMendiola JustinAl-Rajhi AmalRaghuraman KeerthanaSha Sharon JWilson Edward NWyss-Coray TonyWagner Anthony DMaecker Holden TMormino Elizabeth C - To investigate the effect of Agaricus bisporus polysaccharides (ABPs) on Aeromonas salmonicida (A. salmonicida)-induced enteritis in crayfish, this study first established an enteritis model in crayfish via A. salmonicida infection. Subsequently, ABPs at a concentration of 0.5 mg/mL were administered to the enteritis-affected crayfish via anal perfusion at a dosage of 100 μL per individual. The intestinal tissues of the treated crayfish were collected to perform transcriptome analysis and intestinal microbiota composition analysis.Transcriptomic analysis of the crayfish intestines revealed that A. salmonicida infection resulted in the upregulation of genes including FCN2, Hsp22, DDX1, HSPA8, and syntaxin-like, while significantly downregulating the expression of the BCL11A gene. These molecular changes indicated that A. salmonicida infection triggered intestinal inflammation in crayfish, potentially induced intestinal cell apoptosis, and disrupted the composition of the intestinal microbiota. In contrast, ABPs treatment was found to potentially enhance the non-specific immunity of crayfish, exert anti-inflammatory effects, and rebalance the intestinal microbiota composition-collectively contributing to an improved ability of crayfish to resist bacterial infections.The findings of this study not only provide a theoretical basis for the prevention and control of enteritis in crayfish but also offer a viable strategy for early interruption of disease progression caused by A. salmonicida infection in crayfish. With broad application prospects, this research also presents new insights for the management of other diseases in the aquaculture industry. - Source: PubMed
Publication date: 2025/10/28
Zhu XiaWang LuHe HaoYang ZiyangLiu YongtaoAi XiaohuiYao JiayunYang Yibin - - Source: PubMed
Publication date: 2025/07/25
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