Anti_Human, mab KIR2DS4 Source Mouse
- Known as:
- Anti_Human, mab KIR2DS4 Source Mouse
- Catalog number:
- 101-M542
- Product Quantity:
- 100 µg
- Category:
- -
- Supplier:
- Reliatech
- Gene target:
- Anti_Human mab KIR2DS4 Source Mouse
Related genes to: Anti_Human, mab KIR2DS4 Source Mouse
- Gene:
- KIR2DS4 NIH gene
- Name:
- killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
- Previous symbol:
- -
- Synonyms:
- cl-39, KKA3, nkat8, CD158i
- Chromosome:
- 19q13.42
- Locus Type:
- gene with protein product
- Date approved:
- 1997-11-14
- Date modifiied:
- 2016-01-20
Related products to: Anti_Human, mab KIR2DS4 Source Mouse
Related articles to: Anti_Human, mab KIR2DS4 Source Mouse
- The killer-cell immunoglobulin-like receptors (KIR) are a family of activating and inhibitory Class I human leukocyte antigen (HLA-I) binding receptors expressed on natural killer (NK) cells and subsets of T cells. The KIR detect HLA-I molecules in a peptide-dependent manner, with some KIR displaying exquisite peptide specificity. Studying peptide recognition by KIR often uses TAP-deficient cell lines expressing single HLA-I alleles, which are heterogenous and time consuming to generate. Here, we established an alternative approach using peptide-exchange technologies hitherto developed for studying T cell recognition of HLA-I. - Source: PubMed
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Murali Tanusya MLi BeiningHoos EmeryCollinson LucyLong Eric ODushek OmerElliott TimSim Malcolm J W - To identify druggable genes associated with cataract and investigate their functional roles under oxidative stress, thereby providing potential therapeutic targets. - Source: PubMed
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Wu JiahuiYi WangLiu MengtingLi YingliangZhou BoxuanWu ZiyunCao WeiShi QingfengCai XiangkaiXiong Haiwei - The killer-cell immunoglobulin-like receptor () gene cluster exhibits complicated diversity in haplotype content, copy-number variation (CNV), and allelic polymorphism. To date, 2,286 distinct alleles have been released in the IPD-KIR Database. However, little is known about the impact of high-resolution-level allelic polymorphisms on leukemia. Our previous study showed that the genotype carrying more inhibitory genes conferred differential protection against leukemia in the Chinese Southern Han population. Herein, we hypothesized the impact of alleles in the haplotype and cognate human leukocyte antigen (HLA) ligand on leukemia. - Source: PubMed
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