p24 of HIV-1, epitope GATPQDLNTML ANTIBODIES Isotype IgG HOST SPECIES MOUSE
- Known as:
- p24 H. sapiens immunodeficiency virus-1, epitope GATPQDLNTML ANTIBODIES Isotype Immunoglobulin G HOST SPECIES MOUSE
- Catalog number:
- AB006
- Product Quantity:
- 1 mg
- Category:
- -
- Supplier:
- Polim
- Gene target:
- p24 HIV-1 epitope GATPQDLNTML ANTIBODIES Isotype IgG HOST SPECIES MOUSE
Ask about this productRelated genes to: p24 of HIV-1, epitope GATPQDLNTML ANTIBODIES Isotype IgG HOST SPECIES MOUSE
- Gene:
- CERNA2 NIH gene
- Name:
- competing endogenous lncRNA 2 for microRNA let-7b
- Previous symbol:
- -
- Synonyms:
- HOST2
- Chromosome:
- 10q23.1
- Locus Type:
- RNA, long non-coding
- Date approved:
- 2017-04-27
- Date modifiied:
- 2017-07-14
Related products to: p24 of HIV-1, epitope GATPQDLNTML ANTIBODIES Isotype IgG HOST SPECIES MOUSE
Related articles to: p24 of HIV-1, epitope GATPQDLNTML ANTIBODIES Isotype IgG HOST SPECIES MOUSE
- Long noncoding RNAs (lncRNAs) may contribute to the formation of psoriatic lesions. The present study's objective was to identify long lncRNA genes that are differentially expressed in patient samples of psoriasis through computational analysis techniques. By using previously published RNA sequencing data from psoriatic and healthy patients (n = 324), we analysed the differential expression of lncRNAs to determine transcripts of heightened expression. We computationally screened lncRNA transcripts as annotated by GENCODE across the human genome and compared transcription in psoriatic and healthy samples from two separate studies. We observed 54 differentially expressed genes as seen in two independent datasets collected from psoriasis and healthy patients. We also identified the differential expression of LINC01215 and LINC1206 associated with the cell cycle pathway and psoriasis pathogenesis. SH3PXD2A-AS1 was identified as a participant in the STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop. Both the SH3PXD2A-AS1 and CERNA2 genes have already been recognised as part of the IFN-γ signalling pathway regulation. Additionally, EPHA1-AS1, CYP4Z2P and SNHG12 gene upregulation have all been previously linked to inflammatory skin diseases. Differential expression of various lncRNAs affects the pathogenesis of psoriasis. Further characterisation of lncRNAs and their functions are important for developing our understanding of psoriasis. - Source: PubMed
Publication date: 2023/11/15
Stacey Valerie MKõks Sulev - Long non-coding RNAs (lncRNAs) have been the subject of considerable attention in recent years due to their role in gene regulation. However, the function of lncRNAs remains poorly understood, especially in the context of infection with low-risk human papillomaviruses (HPVs). To further understanding on this issue, we investigated lncRNA expression in HPV-induced common warts. - Source: PubMed
Publication date: 2022/11/19
Tarkhan Amneh HAl-Eitan Laith NAlkhatib Rami QAlghamdi Mansour A - Gastric cancer (GC) is the second most common cancer-related mortality worldwide. Mounting evidence has demonstrated that dysregulated long noncoding RNAs (lncRNAs) are involved in the development of GC. LncRNA CERNA2 (competing endogenous lncRNA 2 for microRNA let-7b) was previously found to be upregulated and play an oncogenic role in hepatocellular carcinoma, osteosarcoma and breast cancer. However, the clinical significance and biological functions of CERNA2 in GC remain largely unknown. In this study, we found that CERNA2 expression was significantly increased in GC tissues and cell lines compared to adjacent non-cancerous tissues and normal gastric epithelial cells, respectively. High levels of CERNA2 were correlated with poor clinical parameters and an unfavorable prognosis of GC patients. Moreover, silencing CERNA2 expression effectively inhibited gastric cancer cell growth and induced cell apoptosis . Collectively, our results demonstrate that the up-regulation of CERNA2 is associated with malignant status and poor prognosis in patients with GC, and silencing CERNA2 expression inhibits gastric cancer cell growth and promotes cell apoptosis, suggesting CERNA2 could possibly be a promising diagnostic and treatment target for GC. - Source: PubMed
Publication date: 2018/12/01
Zhang JingjingHan XiaoJiang LeiHan ZhengquanWang Zian - Competing long noncoding RNA 2 (lncRNA 2) for microRNA let-7b (CERNA2) has emerged as an important regulator of tumorigenesis and cancer progression but the clinical value and regulatory function of CERNA2 is yet to be investigated in cervical carcinoma. In our study, we found the CERNA2 expression was obviously increased in cervical carcinoma tissues compared with adjacent normal cervical tissues. In addition, we observed that metastatic lymph nodes exhibited high levels of CERNA2 expression in contrast to primary cervical carcinoma tissues. Furthermore, high CERNA2 expression was associated with advanced clinical stage, lymph node metastasis, distant metastasis poor histological grade, and short overall survival in cervical carcinoma patients. Moreover, high CERNA2 expression acted as an independent unfavorable predictor for overall survival in cervical carcinoma patients. The cell migration and invasion assays in vitro suggested that knockdown of CERNA2 remarkably inhibited cell migration and invasion in cervical carcinoma. In conclusion, CERNA2 functions as an oncogenic lncRNA and may be as a potential therapeutic target in cervical carcinoma. - Source: PubMed
Publication date: 2019/02/21
Wang MinOuyang JianghuaLi Huali - The ribonucleic acids, ccRNA-1 and ceRNA-2, associated with cadang-cadang disease are circular single-stranded molecules comprising 310 +/- 3 nucleotides and 438 +/- 5 nucleotides, respectively; their molecular weights are estimated to be 1.05 and 1.49 x 10(5) daltons. Therefore ceRNA-2 appears not to be a dimer of ccRNA-1, although it is known to have nucleotide sequences in common with ccRNA-1. Differences in the native structure of the two RNAs as determined by length measurements may account for previously described differences in their properties. Both RNAs resemble viroids, but ccRNA-1 is smaller, and ceRNA-2 is larger, than the viroids which have been characterized. - Source: PubMed
Randles J WHatta T