Interferon gamma (IFN g)
Recombinant Human Interferon gamma-1b is a sterile protein product for injection. rHuIFN gis produced by recombinant DNA technology by E.coli carrying a genetically engineered plasmid containing human interferon gamma gene. It is a highly purified protein containing 140 amino acids, and has a molecular weight of approximately16.5kD.
1. Indicated for reducing the frequency and severity of serious infections associated with Chronic Granulomatous Disease.
2. Indicated for delaying time to disease progression in patients with severe, malignant osteopetrosis.
l Pharmaceutical particulars
Sterile, clear, colorless and preservative-free liquid for injection in vials.
Dosage: 1 million IU (0.5ml)/vial
Reference: current Chinese Pharmacopoeia and Internal Requirement
Specific activity: 2.0×107 IU/mg
Purity (HPLC, SDS-PAGE): ≥98%
Active ingredient: Recombinant Human Interferon gamma (IFN gamma)
Inactive ingredients: Succinic acid, Mannitol and Polysorbate-20
l Shelf life and storage conditions
| Finished formulation
|| Store at 2-8℃ for 2 years
| API (Concentrated solution)
|| Store at -70℃ for 12 months