HIV-I RNA Real Time PCR Kit CE
- Known as:
- H. sapiens immunodeficiency virus-I RNA qPCR test kit Kit CE
- Catalog number:
- 09013025
- Product Quantity:
- 25 tests
- Category:
- -
- Supplier:
- RTA
- Gene target:
- HIV- RNA Real Time PCR Kit
Related genes to: HIV-I RNA Real Time PCR Kit CE
- Gene:
- CCNT1 NIH gene
- Name:
- cyclin T1
- Previous symbol:
- HIVE1
- Synonyms:
- CCNT, CYCT1
- Chromosome:
- 12q13.11-q13.12
- Locus Type:
- gene with protein product
- Date approved:
- 1998-04-29
- Date modifiied:
- 2018-02-13
- Gene:
- HIVEP2 NIH gene
- Name:
- human immunodeficiency virus type I enhancer binding protein 2
- Previous symbol:
- -
- Synonyms:
- MBP-2, HIV-EP2, MIBP1, ZAS2, Schnurri-2, ZNF40B
- Chromosome:
- 6q24.2
- Locus Type:
- gene with protein product
- Date approved:
- 1992-10-21
- Date modifiied:
- 2016-10-05
- Gene:
- KCND3 NIH gene
- Name:
- potassium voltage-gated channel subfamily D member 3
- Previous symbol:
- SCA22, SCA19
- Synonyms:
- Kv4.3, KSHIVB
- Chromosome:
- 1p13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1992-10-05
- Date modifiied:
- 2019-04-23
Related products to: HIV-I RNA Real Time PCR Kit CE
Related articles to: HIV-I RNA Real Time PCR Kit CE
- - Source: PubMed
Publication date: 2024/06/28
Badmann SusannCastrop FlorianBrugger MelanieWinkelmann JulianeZech Michael - The contribution of de novo variants as a cause of intellectual disability (ID) is well established in several cohorts reported from the developed world. However, the genetic landscape as well as the appropriate testing strategies for identification of de novo variants of these disorders remain largely unknown in low-and middle-income countries like India. In this study, we delineate the clinical and genotypic spectrum of 54 families (55 individuals) with syndromic ID harboring rare de novo variants. We also emphasize on the effectiveness of singleton exome sequencing as a valuable tool for diagnosing these disorders in resource limited settings. Overall, 46 distinct disorders were identified encompassing 46 genes with 51 single-nucleotide variants and/or indels and two copy-number variants. Pathogenic variants were identified in CREBBP, TSC2, KMT2D, MECP2, IDS, NIPBL, NSD1, RIT1, SOX10, BRWD3, FOXG1, BCL11A, KDM6B, KDM5C, SETD5, QRICH1, DCX, SMARCD1, ASXL1, ASXL3, AKT3, FBN2, TCF12, WASF1, BRAF, SMARCA4, SMARCA2, TUBG1, KMT2A, CTNNB1, DLG4, MEIS2, GATAD2B, FBXW7, ANKRD11, ARID1B, DYNC1H1, HIVEP2, NEXMIF, ZBTB18, SETD1B, DYRK1A, SRCAP, CASK, L1CAM, and KRAS. Twenty-four of these monogenic disorders have not been previously reported in the Indian population. Notably, 39 out of 53 (74%) disease-causing variants are novel. These variants were identified in the genes mainly encoding transcriptional and chromatin regulators, serine threonine kinases, lysosomal enzymes, molecular motors, synaptic proteins, neuronal migration machinery, adhesion molecules, structural proteins and signaling molecules. - Source: PubMed
Publication date: 2023/12/20
Pande ShrutiMajethia PurviNair KarthikRao Lakshmi PriyaMascarenhas SelindaKaur Namanpreetdo Rosario Michelle CNeethukrishna KausthubhamChaurasia AnkurHunakunti BhageshJadhav NaleshXavier SruthyKumar JeevanBhat VivekanandaBhavani Gandham SriLakshmiNarayanan Dhanya LakshmiYatheesha B LPatil Siddaramappa JNampoothiri SheelaKamath NutanAroor ShrikiranBhat Y RameshLewis Leslie ESharma SuvasiniBajaj ShrutiSankhyan NaveenSiddiqui ShahyanNayak Shalini SBielas StephanieGirisha Katta MohanShukla Anju - Mounting evidence indicates that the gut microbiota influences the neurodevelopment and behavior of insects through the gut-brain axis. However, it is currently unclear whether the gut microbiota affect the head profiles and immune pathway in pests. Here, we find that gut bacteria is essential for the immune and neural development of adult Spodoptera frugiperda, which is an extremely destructive agricultural pest worldwide. 16 S rRNA sequencing analysis showed that antibiotics exposure significantly disturbed the composition and diversity of gut bacteria. Further transcriptomic analysis revealed that the adult head transcripts were greatly affected by gut dysbacteriosis, and differently expression genes critical for brain and neural development including A4galt, Tret1, nsun4, Galt, Mitofilin, SLC2A3, snk, GABRB3, Oamb and SLC6A1 were substantially repressed. Interestingly, the dysbacteriosis caused sex-specific differences in immune response. The mRNA levels of pll (serine/threonine protein kinase Pelle), PGRP (peptidoglycan-sensing receptor), CECA (cecropin A) and CECB (cecropin B) involved in Toll and Imd signaling pathway were drastically decreased in treated male adults' heads but not in female adults; however, genes of HIVEP2, ZNF131, inducible zinc finger protein 1-like and zinc finger protein 99-like encoding zinc-finger antiviral protein (ZAP) involved in the interferon (IFNα/β) pathway were significantly inhibited in treated female adults' heads. Collectively, these results demonstrate that gut microbiota may regulate head transcription and impact the S. frugiperda adults' heads through the immune pathway in a sex-specific manner. Our finding highlights the relationship between the gut microbiota and head immune systems of S. frugiperda adults, which is an astonishing similarity with the discoveries of other animals. Therefore, this is the basis for further research to understand the interactions between hosts and microorganisms via the gut-brain axis in S. frugiperda and other insects. - Source: PubMed
Publication date: 2023/12/07
Junrui-Fu Rong ZixiaHuang XimeiWang JunhanLong XiaoyanFeng QiliDeng Huimin - Approximately 80 to 90% of patients with gastric cancer (GC) eventually develop into metastatic GC nowadays,because GC is difficult to be diagnosed at an early stage. GC patients with metastases typically have a poor prognosis. It is necessary to explore a potential prognostic marker in metastatic GC. - Source: PubMed
Sha RulaZhang JiamingMeng FanjieZhaori Getu - Intellectual development disorder, autosomal dominant 43 (MRD43) is an autosomal dominant disorder caused by heterozygous mutations in the gene. In this report, we describe a case of a 4-year-old boy with global development delay, hypotonia, and dysmorphic features, in whom the finding of a heterozygous nonsense pathogenic variant in exon 5 of [c.2827C>T p. (Arg943*)] through WES established a MRD43 diagnosis. Our patient's phenotype overlaps with other MRD43 descriptions in the literature. Unlike previously reported cases, where the condition was almost invariably , the healthy mother in this case presented mosaicism for the pathogenic variant. Thus, the recurrence risk increased significantly from 1% to up to 50%. The description of a variant inherited for MDR43 is singular in the literature and this description highlights the importance of parental studies for accurate genetic counseling, particularly for family planning. - Source: PubMed
Publication date: 2023/06/27
Abreu MariaBranco TiagoFigueiroa SóniaReis Cláudia Falcão