HemoVoid Kit removes hemoglobin with 98% efficiency following a simple 30 min protocol using mild buffers. The kit is based on a silica-based protein enrichment matrix, which could be used for extraction from red cell lysates for RBC proteomics, hemolyzed serum; native enzyme activity is retained in elution fractions thanks to the mild conditions, which are required in the protocol. What is more, the kit Hemovoid is compatible with for protein quantitation with Mass Spectrometry. The kit is designed for 5 reations. red cell lysates for proteomic studies of the preserved enzymes that are retained in elution fractions.