E. coli Host Cell Protein Standards
- Known as:
- E. coli Host Cell Protein Standards
- Catalog number:
- AB000106
- Product Quantity:
- 50
- Category:
- -
- Supplier:
- Array Bridge
- Gene target:
- . coli Host Cell Protein Standards
Related genes to: E. coli Host Cell Protein Standards
- Gene:
- FCN2 NIH gene
- Name:
- ficolin 2
- Previous symbol:
- -
- Synonyms:
- P35, FCNL, EBP-37, ficolin-2
- Chromosome:
- 9q34.3
- Locus Type:
- gene with protein product
- Date approved:
- 1996-07-11
- Date modifiied:
- 2016-10-05
Related products to: E. coli Host Cell Protein Standards
Related articles to: E. coli Host Cell Protein Standards
- Acute myocardial infarction (AMI) is a critical cardiovascular event characterized by sudden coronary blood flow interruption, leading to myocardial ischemia and necrosis. Despite advances in acute therapeutic measures, understanding the metabolic damage related to AMI, particularly through specific protein expressions, remains limited. This study utilized Olink cardiovascular metabolomics technology to explore cardiovascular metabolism-related protein biomarkers associated with AMI, aiming to address the clinical need for early diagnosis and targeted therapy. - Source: PubMed
Publication date: 2025/02/22
Tan XinWang XiangyuXu ShuaiZeng YiyaoZhang GeXu AnchenJiang YufengJiang HeziSong YahuiFan JiliFu YangjunBo XiaohongFan HuiminZhou Yafeng - Proteomic evaluation of plasma samples could accelerate the identification of novel Alzheimer's disease (AD) biomarkers. We evaluated the novel NUcleic acid Linked Immuno-Sandwich Assay (NULISA) proteomic method in an ethnically diverse cohort. - Source: PubMed
Zeng XuemeiSehrawat AnuradhaLafferty Tara KChen YijunRawat MahikaKamboh M IlyasVillemagne Victor LLopez Oscar LCohen Ann DKarikari Thomas K - This study was to explore the relationship between plasma exosomes and Acute myocardial infarction (AMI). - Source: PubMed
Publication date: 2025/01/01
Xu ShashaZhai YiWang ChenZhang YangLiu XiaoweiJiang JianjunMi Yafei - Parkinson's disease (PD) is a complex neurodegenerative disease with unclear pathogenesis. Some recent studies have shown that there is a close relationship between PD and ferroptosis. We aimed to identify the ferroptosis-related genes (FRGs) and construct competing endogenous RNA (ceRNA) networks to further assess the pathogenesis of PD. - Source: PubMed
Publication date: 2024/12/31
Li TaoleGuo Jifeng - To investigate the effect of single nucleotide polymorphism (SNP) of FCN gene on the susceptibility of pre-eclampsia (PE) in Han nationality pregnant women. A total of 274 PE pregnant women (PE group) and 154 healthy pregnant women (control group) admitted to Boai Hospital of Zhongshan, Affiliated Hospital to Southern Medical University from October 2020 to October 2022 were collected. The general information, medical history, reproductive history, blood pressure, body mass index and blood biochemical indicators before delivery were compared between the two groups. Twenty-three SNP loci of FCN gene family were genotyped by time-of-flight mass spectrometry, and the serum levels of ficolins (ficolin-1, -2 and -3) were detected by enzyme-linked immunosorbent assay. (1) Compared with the control group, the body mass index, mean arterial pressure, gestational age at delivery, blood urea nitrogen, alanine aminotransferase, aspartate aminotransferase, direct bilirubin, albumin, and C-reactive protein in the PE group were significantly higher than those in the control group (all <0.05). The levels of N-terminal pro-B type natriuretic peptide (NT-proBNP), placental growth factor (PlGF) and human soluble vascular endothelial growth factor receptor-1 (sFlt-1) were significantly different between the two groups (all <0.05). (2) Among the 23 SNP loci in FCN gene family, 18 loci were in Hardy-Weinberg genetic equilibrium, including 5 loci in FCN1 gene, 10 loci in FCN2 gene, and 3 loci in FCN3 gene. Five loci that did not conform to Hardy-Weinberg genetic equilibrium were not included in the subsequent analysis. Compared with the control group, the genotype distribution of 3 loci of FCN2 gene (rs7872508, rs11103563, rs73664188) and 1 locus of FCN3 gene (rs3813800) in the PE group were significantly different (all <0.05). After Bonferroni correction, only the genotype distribution of rs7872508 and rs73664188 in FCN2 gene were statistically different between the PE group and the control group (all <0.05). Further analysis showed that for the rs7872508 locus of FCN2 gene, compared with GG genotype, genotype GT (=3.025, 95%: 1.080-8.471) and TT (=4.777, 95%: 1.758-12.979) both significantly increased the risk of PE (both <0.05). For rs73664188 locus of FCN2 gene, compared with TT genotype, genotype TC (=0.510, 95%: 0.334-0.778) significantly reduced the risk of PE (<0.05). (3) Compared with the control group, the serum levels of ficolin-1 and ficolin-2 in pregnant women in the PE group were significantly reduced (both <0.05), while the level of ficolin-3 showed no significant change (=0.271). Correlation analysis showed that the serum levels of ficolin-2 in pregnant women in the PE group were significantly positively correlated with PlGF level (=0.321, <0.001), and significantly negatively correlated with sFlt-1 level (=-0.187, =0.002) and NT-proBNP level (=-0.392, <0.001). Further analysis revealed that the serum levels of ficolin-2 in pregnant women of the PE group with GT and TT genotypes at rs7872508 locus of FCN2 gene were significantly reduced (both <0.05), while the serum level of ficolin-2 in pregnant women of the PE group with TC genotype at the rs73664188 locus were significantly increased (<0.05). The SNP of FCN2 gene in FCN gene family might be related to the susceptibility to PE and have an effect on serum ficolin-2 level in PE pregnant women. - Source: PubMed
Tan J YTan Y LYang BYang WYuan C LMi X JCai F EGan Y JHe Y J