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TGFB1 antibody product offer - Gentaur Molecular Products

TGFB1 antibody

Price:

523.23 €

Known as:: TGFB1 (anti-)
Catalog number:: 70r-20793
Product Quantity:: USD
Category:: -
Supplier:: Fitzgerald industries international
Gene target:: TGFB1 antibody

Ask about this product

Related genes to: TGFB1 antibody

Gene:: TGFB1 ^{NIH gene}
Name:: transforming growth factor beta 1
Previous symbol:: TGFB, DPD1
Synonyms:: CED, TGFbeta
Chromosome:: 19q13.2
Locus Type:: gene with protein product
Date approved:: 2001-06-22
Date modifiied:: 2019-04-16

Gene:: TSC22D1 ^{NIH gene}
Name:: TSC22 domain family member 1
Previous symbol:: TGFB1I4
Synonyms:: TSC22, MGC17597
Chromosome:: 13q14.11
Locus Type:: gene with protein product
Date approved:: 2004-04-16
Date modifiied:: 2016-10-05

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Related articles to: TGFB1 antibody

Posttranscriptional regulation of TSC-22 (TGF-beta-stimulated clone-22) gene by TGF-beta 1.
TSC-22 gene was composed of three exons and its length was approximately 5.5 kb including 2.9 kb promoter region. The transcription starting site was located at 7 and 29 bp downstream from TATA box. Promoter analysis revealed that 2146 bp of TSC-22 promoter was activated by several differentiation inducing drugs. Although originally TSC-22 was isolated as a TGF-beta-inducible gene, TSC-22 promoter was not activated by the enhanced TGF-beta signaling. We found 3 copies of the Shaw-Kamens sequence (AUUUA) in the human TSC-22 mRNA 3'-UTR and identified three proteins (40, 20, and 15 kDa) which bound to this. Only the 40 kDa protein-RNA complex was decreased by treatment with TGF-beta 1. Moreover, the TSC-22 mRNA 3'-UTR destabilized the heterologous luciferase mRNA, but the destabilization was recovered with TGF-beta 1. These observations suggest that up-regulation of TSC-22 mRNA by TGF-beta 1 is achieved by mRNA stabilization, but not by transcriptional activation. - Source: PubMed
Uchida DaisukeOmotehara FumieNakashiro Koh-ichiTateishi YoshihisaHino SatoshiBegum Nasima-MilaFujimori TakahiroKawamata Hitoshi