CCL25_PIG CCL25 ELISA tesk kit
- Known as:
- CCL25_PIG CCL25 Enzyme-linked immunosorbent assay test tesk reagent
- Catalog number:
- gen16075
- Product Quantity:
- 1
- Category:
- Peptides
- Supplier:
- Other suppliers
- Gene target:
- CCL25_PIG CCL25 ELISA tesk kit
Related genes to: CCL25_PIG CCL25 ELISA tesk kit
- Gene:
- CCL25 NIH gene
- Name:
- C-C motif chemokine ligand 25
- Previous symbol:
- SCYA25
- Synonyms:
- TECK, Ckb15
- Chromosome:
- 19p13.2
- Locus Type:
- gene with protein product
- Date approved:
- 1997-11-14
- Date modifiied:
- 2016-03-01
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- To investigate the effect of on thymic cortical regeneration in rapamycin-treated mice and its underlying mechanisms. - Source: PubMed
Publication date: 2026/06/08
Xu XieShu YaoyingGao Jianli - Immune dysregulation plays a critical role in idiopathic pulmonary fibrosis (IPF), but the mechanisms underlying this dysregulation remain unclear. - Source: PubMed
Publication date: 2026/06/03
Zhao JiaxingLiu ZenghuiKuang LuDong AijiaGong HeyueYin HuayuWu ShaoguoLiu DabinLiu XuehuiLiu ShuyanWu Limei - Intraepithelial lymphocytes (IELs) are among the largest lymphocyte populations in the body and play a crucial role in maintaining the integrity of epithelial barriers at mucosal sites, which are highly immunostimulatory. Therefore, understanding how these cells are generated, localized within the epithelium, and contribute to barrier immunity is essential. Although most research on IEL biology has focused on the small intestine, IELs are also present in the large intestinal epithelium. Additionally, the homing receptor-ligand pairs that regulate T cell localization in the lamina propria beneath the epithelium differ between the small and large intestines: CCL25-CCR9 in the small intestine and C10ORF99-GPR15 in the large intestine. CCL25-CCR9 is also necessary for proper localization of IELs in the small intestine, but the mechanisms controlling IEL localization in the large intestine remain unknown. Here, we demonstrate that the C10ORF99-GPR15 pathway is crucial for the presence of TCR + natural IELs in the large intestinal epithelium, a process that requires epithelium-derived C10ORF99 (GPR15L). - Source: PubMed
Publication date: 2026/06/01
O'Connor Gerald JChoi Jihae CVan Nguyen TKlutkoski Anthony MRobertson Lucia CKim Sangwon V - The chemokine receptor CCR9 regulates thymus colonization by T progenitors and intestinal accumulation of TCRγδ+ intraepithelial lymphocytes (IELs). CCR9-ligand chemokine CCL25 is expressed predominantly in the thymus and the small intestine. By engineering tissue-specific CCL25-deficient mice, we demonstrate that CCL25 locally produced by thymic and intestinal epithelial cells individually supports developing T cell localization in the thymus and TCRγδ+ IEL accumulation in the small intestine, respectively. Our results also reveal that thymic epithelial CCL25 facilitates T cell positive selection in the thymic cortex. We further find that intestinal epithelial CCL25 promotes nutrient sensing in the small intestine. These results indicate that epithelial CCL25 directs thymic T cell development and intestinal homeostasis in a tissue-specific paracrine manner. - Source: PubMed
Publication date: 2026/05/12
Li JieYang Mei-TingMatsuda-Lennikov MamiKalle-Youngoue FelixUshio AyaKondo KentaGluckman MelecaBando KanaAbe TakayaTakada KensukeKelly Michael CCastro Martinez FelipeChen ZuojiaWu ChuanTakahama Yousuke - This study conducted a meta-analysis across three large European cohorts (UKBB, FinnGen, and REPAIR), including 12,660 rheumatoid arthritis (RA) cases, 2,446 radiographic axial spondyloarthritis (r-axSpA) cases, and over 530,000 shared controls. - Source: PubMed
Publication date: 2026/04/23
Cabrera-Serrano Antonio JoséCarretero-Fernández MaríaPérez-Rojo BegoñaTer Horst RobCañadas-Garre MarisaCanhão HelenaQuartuccio LucaSorensen Signe BGlintborg BenteFilipescu IleanaPérez-Pampin EvaConesa-Zamora PabloSwierkot Jerzyden Broeder Alfons Ade Vita SalvatoreBrix Petersen Eva RabingLi YangCoenen Marieke J HBogunia-Kubik KatarzynaAndersen VibekeFonseca João EuricoLund Hetland MereteLópez Nevot Miguel ÁngelLópez-Medina ClementinaReyes-Zurita Fernando JesúsNetea Mihai GEscudero AlejandroCáliz RafaelCollantes-Estévez EduardoSánchez-Maldonado José ManuelSainz Juan