rabbit IgG against mouse IgG3 (subclass specific), conjugated with TRITC

Price:
567 EUR
680 USD
470 GBP
known as: rabbit IgG mouse IgG3 (subclass specific), conjugated TRITC
Catalog number: genta-RAM/IgG3/TRITC
Product Quantity: 1 ml
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Gene target: igg3 subclass specific conjugated tritc

More details: rabbit IgG against mouse IgG3 (subclass specific), conjugated with TRITC

wikipedia:

IgG antibodies are large molecules of about 150kilodalton made of four peptide chains. It contains two identical class γ heavy chains of about 50 kDa and two identical light chains of about 25 kDa, thus a tetrameric quaternary structure. The two heavy chains are linked to each other and to a light chain each by disulfide bonds. The resulting tetramer has two identical halves, which together form the Y-like shape. Each end of the fork contains an identicalantigen binding site. The various regions and domains of a typical IgG are depicted in the figure to the left. The Fc regions of IgGs bear a highly conserved N-glycosylation site. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and α-2,6-linked sialic acid residues.

The various regions and domains of a typical IgG

Subclasses

There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant).

Name Percent Crosses placenta easily Complement activator Binds to Fc receptor on phagocytic cells Half Life
IgG1 66% yes (1.47)* second-highest high affinity 21 days
IgG2 23% no (0.8)* third-highest extremely low affinity 21 days
IgG3 7% yes (1.17)* highest high affinity 7 days
IgG4 4% yes (1.15)* no intermediate affinity 21 days
* Quota cord/maternity concentrations blood. Based on data from a Japanese study on 228 mothers.

Related genes to: rabbit IgG against mouse IgG3 (subclass specific), conjugated with TRITC

Symbol : IGG NIH gene
dbXrefs : AnimalQTLdb:17939
chromosome : 2
map location : 2 0.2 cM
description : Immunoglobulin G level
type of gene : unknown
Modification date : 2015-01-24

Related Pathways to: rabbit IgG against mouse IgG3 (subclass specific), conjugated with TRITC

Gene about :IgG3
Pathway :Hs Allograft Rejection
IgG3
Gene about :IgG
Pathway :Mm Microglia Pathogen Phagocytosis Pathway
IgG

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